N-(p-toluenesulfonyl)-α-dehydrocyclohexylglycine

Base Information

• Chemical Name: N-(p-toluenesulfonyl)-α-dehydrocyclohexylglycine
• CAS No.: 863912-70-3
• Molecular Formula: C₁₅H₁₉NO₄S
• Molecular Weight: 309.386
• Mol file: 863912-70-3.mol

Synonyms:N-(p-toluenesulfonyl)-α-dehydrocyclohexylglycine

Chemical Property of N-(p-toluenesulfonyl)-α-dehydrocyclohexylglycine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N-(p-toluenesulfonyl)-α-dehydrocyclohexylglycine

There total 1 articles about N-(p-toluenesulfonyl)-α-dehydrocyclohexylglycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

2-cyclohexyl-2-oxoethanoic acid (4354-49-8) + toluene-4-sulfonamide (70-55-3) → N-(p-toluenesulfonyl)-α-dehydrocyclohexylglycine (863912-70-3)

Guidance literature:

With methanesulfonic acid; In toluene; for 24h; Heating;

DOI:10.1021/ol050869s

Reference yield: 100.0%

N-(p-toluenesulfonyl)-α-dehydrocyclohexylglycine (863912-70-3) → N-(p-toluenesulfonyl)cyclohexylglycine

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃; under 2068.59 Torr;

DOI:10.1021/ol050869s

Reference yield: 99.0%

N-(p-toluenesulfonyl)-α-dehydrocyclohexylglycine (863912-70-3) → (R)-2-cyclohexyl-2-((4-methylphenyl)sulfonamido)acetic acid

Guidance literature:

With hydrogen; C₄₆H₄₆ClP₂RuS₂⁽¹⁺⁾*Cl^(1-); In ethanol; at 25 ℃; for 24h; under 5414.51 Torr; Product distribution / selectivity;

upstream raw materials:

2-cyclohexyl-2-oxoethanoic acid

toluene-4-sulfonamide

Refernces

• 1、 -. "PROCESS FOR MAKING N-SULFONATED-AMINO ACID DERIVATIVES". Page/Page column 30. . Retrieved 2008/06/13.