N-(3-cyclohexyl-2-propynyl)-N-methyl-1-naphthalenemethanamine

Base Information

• Chemical Name: N-(3-cyclohexyl-2-propynyl)-N-methyl-1-naphthalenemethanamine
• CAS No.: 98978-39-3
• Molecular Formula: C₂₁H₂₅N
• Molecular Weight: 291.436
• Mol file: 98978-39-3.mol

Synonyms:N-(3-cyclohexyl-2-propynyl)-N-methyl-1-naphthalenemethanamine

Chemical Property of N-(3-cyclohexyl-2-propynyl)-N-methyl-1-naphthalenemethanamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(3-cyclohexyl-2-propynyl)-N-methyl-1-naphthalenemethanamine

There total 2 articles about N-(3-cyclohexyl-2-propynyl)-N-methyl-1-naphthalenemethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2-cyclohexylacetylene (931-48-6) + N-methyl-1-naphthalenemethylamine (14489-75-9) → N-(3-cyclohexyl-2-propynyl)-N-methyl-1-naphthalenemethanamine (98978-39-3)

Guidance literature:

With zinc(II) chloride; In 1,4-dioxane; Heating;

DOI:10.1021/jm00151a019

Reference yield:

1-Chloromethylnaphthalene (86-52-2) → N-(3-cyclohexyl-2-propynyl)-N-methyl-1-naphthalenemethanamine (98978-39-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / ethanol / Ambient temperature

2: 65 percent / ZnCl₂ / dioxane / Heating

With zinc(II) chloride; In 1,4-dioxane; ethanol;

DOI:10.1021/jm00151a019

Reference yield: 60.0%

N-(3-cyclohexyl-2-propynyl)-N-methyl-1-naphthalenemethanamine (98978-39-3) → (E)-(3-cyclohexyl-2-propenyl)-N-methyl-1-naphthalenemethanamine (98978-09-7)

Guidance literature:

With diisobutylaluminium hydride; In toluene; at 40 ℃;

DOI:10.1021/jm00151a019

upstream raw materials:

formaldehyd

2-cyclohexylacetylene

N-methyl-1-naphthalenemethylamine

1-Chloromethylnaphthalene

Downstream raw materials:

(E)-(3-cyclohexyl-2-propenyl)-N-methyl-1-naphthalenemethanamine