2-Amino-5,5-diphenyl-1,3-thiazol-4-one

Base Information

Chemical Name:2-Amino-5,5-diphenyl-1,3-thiazol-4-one
CAS No.:4694-95-5
Molecular Formula:C15H12 N2 O S
Molecular Weight:268.339
Hs Code.:
NSC Number:108778
DSSTox Substance ID:DTXSID70296317
ChEMBL ID:CHEMBL2142292
Mol file:4694-95-5.mol

Synonyms:4694-95-5;MLS002704090;NSC 108778;NSC108778;CHEMBL2142292;DTXSID70296317;NSC-108778;SMR001570797

Suppliers and Price of 2-Amino-5,5-diphenyl-1,3-thiazol-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 2-Amino-5,5-diphenyl-1,3-thiazol-4-one

Chemical Property:

Vapor Pressure:4.83E-08mmHg at 25°C
Boiling Point:442.9°Cat760mmHg
Flash Point:221.7°C
Density:1.29g/cm³
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:268.06703418
Heavy Atom Count:19
Complexity:364

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2(C(=O)N=C(S2)N)C3=CC=CC=C3

Technology Process of 2-Amino-5,5-diphenyl-1,3-thiazol-4-one

There total 7 articles about 2-Amino-5,5-diphenyl-1,3-thiazol-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 7475-56-1
chloro(diphenyl)acetic acid

: 17356-08-0
thiourea

: 4694-95-5
2-amino-5,5-diphenyl-thiazol-4-one

: 76-93-7
Benzilic acid

Guidance literature:: With ethanol; Hydrolysieren des Reaktionsprodukts mit wss. NH₃;

Reference yield:

: 7475-56-1
chloro(diphenyl)acetic acid

: 17356-08-0
thiourea

: 4694-95-5
2-amino-5,5-diphenyl-thiazol-4-one

Guidance literature:: With sodium acetate; In acetic acid; for 0.5h; Heating;
DOI:10.1016/S0040-4020(01)93401-5

Reference yield:

: 76-89-1
methyl benzilate

: 4694-95-5
2-amino-5,5-diphenyl-thiazol-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: POCl₃ / 2 h / 70 °C

2: butan-1-ol / 6 h / 110 °C

With trichlorophosphate; In butan-1-ol;
DOI:10.1248/cpb.30.3601