Acetic acid (1R,2S)-1,2-dimethyl-3-phenylsulfanyl-propyl ester

Base Information

• Chemical Name: Acetic acid (1R,2S)-1,2-dimethyl-3-phenylsulfanyl-propyl ester
• CAS No.: 187671-48-3
• Molecular Formula: C₁₃H₁₈O₂S
• Molecular Weight: 238.351
• Mol file: 187671-48-3.mol

Synonyms:Acetic acid (1R,2S)-1,2-dimethyl-3-phenylsulfanyl-propyl ester

Chemical Property of Acetic acid (1R,2S)-1,2-dimethyl-3-phenylsulfanyl-propyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of Acetic acid (1R,2S)-1,2-dimethyl-3-phenylsulfanyl-propyl ester

There total 9 articles about Acetic acid (1R,2S)-1,2-dimethyl-3-phenylsulfanyl-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

vinyl acetate (108-05-4,9003-20-7) + 3-methyl-4-(phenylsulfanyl)butan-2-ol → Acetic acid (1R,2S)-1,2-dimethyl-3-phenylsulfanyl-propyl ester (187671-48-3) + (2S,3S)-3-methyl-4-(phenylsulfanyl)butan-2-ol (628315-68-4)

Guidance literature:

With 3 A molecular sieve; carrier fixed Candida antarctica lipase B; In n-heptane; at 25 ℃;

DOI:10.1016/j.tetasy.2004.07.049

Reference yield: 42.0%

vinyl acetate (108-05-4,9003-20-7) + (2R)-3-methyl-4-(phenylthio)-2-butanol → (2R,3R)-3-methyl-4-(phenylsulfanyl)butan-2-ol + Acetic acid (1R,2S)-1,2-dimethyl-3-phenylsulfanyl-propyl ester (187671-48-3)

Guidance literature:

With 3 A molecular sieve; immobilised Candida antarctica lipase A; In n-heptane; at 25 ℃;

DOI:10.1016/j.tetasy.2004.07.049

Reference yield: 40.0%

Acetic acid (R)-1,2-dimethyl-3-phenylsulfanyl-propyl ester → (2R)-3-methyl-4-(phenylthio)-2-butanol + Acetic acid (1R,2S)-1,2-dimethyl-3-phenylsulfanyl-propyl ester (187671-48-3)

Guidance literature:

With phosphate buffer; Candida antarctica lipase; florisil; In acetone; at 20 ℃; for 11h; pH=7.0;

DOI:10.1246/bcsj.70.483

upstream raw materials:

vinyl acetate

(S)-(+)-2-methyl-3-(phenylthio)propan-1-ol

(S)-2-methyl-3-(phenylsulfanyl)propanoic acid methyl ester

diphenyldisulfane