Technology Process of methyl 1-([1,1'-biphenyl]-4-yl)-2-formylcyclopropanecarboxylate
There total 4 articles about methyl 1-([1,1'-biphenyl]-4-yl)-2-formylcyclopropanecarboxylate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(E)-methyl 1-([1,1'-biphenyl]-4-yl)-2-styrylcyclopropanecarboxylate;
With
ozone;
In
dichloromethane;
at -78 ℃;
With
triphenylphosphine;
In
dichloromethane;
at 20 ℃;
for 2h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: acetyl chloride / 0 - 20 °C / Inert atmosphere
2.1: 4-acetamidobenzenesulfonyl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / acetonitrile / 0 - 20 °C / Inert atmosphere
3.1: dirhodium tetraacetate / toluene / 3 h / 20 °C / Inert atmosphere
4.1: ozone / dichloromethane / -78 °C
4.2: 2 h / 20 °C
With
4-acetamidobenzenesulfonyl azide; ozone; 1,8-diazabicyclo[5.4.0]undec-7-ene; acetyl chloride;
dirhodium tetraacetate;
In
dichloromethane; toluene; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 4-acetamidobenzenesulfonyl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / acetonitrile / 0 - 20 °C / Inert atmosphere
2.1: dirhodium tetraacetate / toluene / 3 h / 20 °C / Inert atmosphere
3.1: ozone / dichloromethane / -78 °C
3.2: 2 h / 20 °C
With
4-acetamidobenzenesulfonyl azide; ozone; 1,8-diazabicyclo[5.4.0]undec-7-ene;
dirhodium tetraacetate;
In
dichloromethane; toluene; acetonitrile;
![(E)-methyl 1-([1,1'-biphenyl]-4-yl)-2-styrylcyclopropanecarboxylate](/Databaselist/images/loading.webp)
