2-(2-acetoxyethyl)-1,4-diacetylcyclohexane

Base Information

• Chemical Name: 2-(2-acetoxyethyl)-1,4-diacetylcyclohexane
• CAS No.: 86374-41-6
• Molecular Formula: C₁₄H₂₂O₄
• Molecular Weight: 254.326
• Mol file: 86374-41-6.mol

Synonyms:2-(2-acetoxyethyl)-1,4-diacetylcyclohexane

Chemical Property of 2-(2-acetoxyethyl)-1,4-diacetylcyclohexane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2-acetoxyethyl)-1,4-diacetylcyclohexane

There total 4 articles about 2-(2-acetoxyethyl)-1,4-diacetylcyclohexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1S,2S,4R)-2-Bicyclo[2.2.2]oct-5-en-2-yl-ethanol (86420-17-9) → 2-(2-acetoxyethyl)-1,4-diacetylcyclohexane (86374-41-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 99 percent / pyridine / Ambient temperature

2: 93 percent / sodium metaperiodate, ruthenium trichloride hydrate / acetone; H₂O / Ambient temperature

3: 95.7 percent / thionyl chloride, triethylamine / benzene / 3 h / Heating

4: 8.5 g / cuprous iodide / diethyl ether / -40 deg C -> room temperature

With ruthenium trichloride; sodium periodate; copper(l) iodide; thionyl chloride; triethylamine; In pyridine; diethyl ether; water; acetone; benzene;

DOI:10.1021/ja00355a028

Reference yield:

2-(2-acetoxyethyl)bicyclo<2.2.2>oct-5-ene (86374-39-2) → 2-(2-acetoxyethyl)-1,4-diacetylcyclohexane (86374-41-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 93 percent / sodium metaperiodate, ruthenium trichloride hydrate / acetone; H₂O / Ambient temperature

2: 95.7 percent / thionyl chloride, triethylamine / benzene / 3 h / Heating

3: 8.5 g / cuprous iodide / diethyl ether / -40 deg C -> room temperature

With ruthenium trichloride; sodium periodate; copper(l) iodide; thionyl chloride; triethylamine; In diethyl ether; water; acetone; benzene;

DOI:10.1021/ja00355a028

Reference yield:

2-(2-acetoxyethyl)cyclohexane-1,4-dicarboxylic acid (86391-80-2) → 2-(2-acetoxyethyl)-1,4-diacetylcyclohexane (86374-41-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 95.7 percent / thionyl chloride, triethylamine / benzene / 3 h / Heating

2: 8.5 g / cuprous iodide / diethyl ether / -40 deg C -> room temperature

With copper(l) iodide; thionyl chloride; triethylamine; In diethyl ether; benzene;

DOI:10.1021/ja00355a028

upstream raw materials:

methyllithium

2-(2-acetoxyethyl)cyclohexane-1,4-dicarboxyl chloride

(1S,2S,4R)-2-Bicyclo[2.2.2]oct-5-en-2-yl-ethanol

2-(2-acetoxyethyl)bicyclo<2.2.2>oct-5-ene

Downstream raw materials:

2,5-diacetylcyclohexaneacetaldehyde