(20S)-20-Dimethylamino-5α-pregnan-3β-ol

Base Information

• Chemical Name: (20S)-20-Dimethylamino-5α-pregnan-3β-ol
• CAS No.: 474-51-1
• Molecular Formula: C23H41NO
• Molecular Weight: 347.57774
• Mol file: 474-51-1.mol

Synonyms:(3S,5S,8R,9S,10S,13S,14S,17S)-17-((S)-1-Dimethylamino-ethyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-ol;Funtuphyllamin C;20αF-dimethylamino-5α-pregnan-3β-ol;20α(F)-Dimethylamino-5α-pregnan-(3β)-ol;20α-Dimethylamino-5α-pregnan-3β-ol;20α-Dimethylamino-5α-pregnan-ol-(3β);Funtuphyllamin-C;

Chemical Property of (20S)-20-Dimethylamino-5α-pregnan-3β-ol

Chemical Property:

• PSA: 23.47000
• LogP: 4.95630

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (20S)-20-Dimethylamino-5α-pregnan-3β-ol

There total 15 articles about (20S)-20-Dimethylamino-5α-pregnan-3β-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3β-acetoxy-5α-pregnan-20-one oxime (56909-64-9) → 20α-dimethylamino-5α-pregnan-3β-ol (474-51-1)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium; ethanol / und Erhitzen des Reaktionsprodukts mit wss. Formaldehyd und Ameisensaeure und anschliessenden Behandeln mit Acetanhydrid und Pyridin

2: aqueous K₂CO₃

With ethanol; sodium; potassium carbonate;

Reference yield:

3β-acetoxy-20αF-dimethylamino-5α-pregnane (1173-08-6) → 20α-dimethylamino-5α-pregnan-3β-ol (474-51-1)

Guidance literature:

With potassium carbonate;

Reference yield:

pregnenolone acetate (906-83-2) → 20α-dimethylamino-5α-pregnan-3β-ol (474-51-1)

Guidance literature:

Multi-step reaction with 3 steps

1: pyridine; hydroxylamine hydrochloride

2: sodium; ethanol / und Erhitzen des Reaktionsprodukts mit wss. Formaldehyd und Ameisensaeure und anschliessenden Behandeln mit Acetanhydrid und Pyridin

3: aqueous K₂CO₃

With pyridine; ethanol; hydroxylamine hydrochloride; sodium; potassium carbonate;

upstream raw materials:

3β-acetoxy-20α_F-dimethylamino-5α-pregnane

3β-acetoxy-20(S)-5α-bisnorcholanic acid

formaldehyd

20α-amino-5α-pregan-3β-ol