3-Nitropropionic acid

Base Information

Chemical Name:3-Nitropropionic acid
CAS No.:504-88-1
Molecular Formula:C3H5 N O4
Molecular Weight:119.077
Hs Code.:2915900090
European Community (EC) Number:208-003-0
NSC Number:64266
UN Number:2811
UNII:QY4L0FOX0D
DSSTox Substance ID:DTXSID1020982
Nikkaji Number:J12.998D,J1.669.223I
Wikipedia:Beta-Nitropropionic_acid
Wikidata:Q223104
Metabolomics Workbench ID:46456
ChEMBL ID:CHEMBL451226
Mol file:504-88-1.mol

Synonyms:3-nitropropanoic acid;3-nitropropionate;3-nitropropionic acid;3-NP acid;beta-nitropropionic acid;propionate 3-nitronate

Suppliers and Price of 3-Nitropropionic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
3-Nitropropionic acid
50mg
$ 240.00

Usbiological
3-Nitropropionic acid
50mg
$ 276.00

TRC
3-Nitropropionic acid
5g
$ 425.00

Tocris
3-Nitropropionic acid ≥97%(HPLC)
50
$ 49.00

Sigma-Aldrich
3-Nitropropionic acid
50mg
$ 66.90

Sigma-Aldrich
3-Nitropropionic acid ≥97%
1g
$ 85.40

Sigma-Aldrich
3-Nitropropionic acid ≥97%
10g
$ 512.00

Oakwood
3-Nitropropionic acid
25g
$ 495.00

Oakwood
3-Nitropropionic acid
5g
$ 125.00

Oakwood
3-Nitropropionic acid
250mg
$ 25.00

Total 46 raw suppliers

Chemical Property of 3-Nitropropionic acid

Chemical Property:

Appearance/Colour:gold crystalline solid
Vapor Pressure:0.000221mmHg at 25°C
Melting Point:68-70 °C(lit.)
Refractive Index:1.4940 (estimate)
Boiling Point:303°Cat760mmHg
PKA:3.66±0.10(Predicted)
Flash Point:148.4°C
PSA：83.12000
Density:1.393g/cm³
LogP:0.26100
Storage Temp.:2-8°C
Solubility.:alcohol: 100 mg/mL, may be light yellow
XLogP3:-0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:119.02185764
Heavy Atom Count:8
Complexity:104
Transport DOT Label:Poison

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-Nitropropionic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): 1759889
Hazard Codes:T
Statements: 25-36/37/38
Safety Statements: 26-45

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Biological Agents -> Mycotoxins
Canonical SMILES:C(C[N+](=O)[O-])C(=O)O
Recent ClinicalTrials:Mechanism(s) Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 1
Uses antineoplastic 3-Nitropropionic acid has been used:to generate multiple system atropy-parkinsoniam (MSA-P) model in rat to evaluate its effect on embryonic striatal and mesencephalic graftsto inject into the nigrostriatal dopaminergic pathway in rats in order to examine its specific effects on the dopamine systemas succinate dehydrogenase (SDH) inhibitor for LUHMES neurons and cell lines

Technology Process of 3-Nitropropionic acid

There total 10 articles about 3-Nitropropionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 930-21-2
2-azetidinone

: 504-88-1
3-nitropropionic acid

Guidance literature:: With methyltrifluoromethyldioxirane; In water; at 0 ℃; for 0.5h;
DOI:10.1016/j.tetlet.2012.11.074

Reference yield: 96.0%

: 58657-26-4
3-nitropropionaldehyde

: 504-88-1
3-nitropropionic acid

Guidance literature:: With sodium chlorite; sodium dihydrogenphosphate; dihydrogen peroxide; In water; acetonitrile; at 25 ℃;
DOI:10.1081/SCC-100000587