2-(p-trifluoromethylphenyl)-4-(2-benzyloxy-naphthalen-1-yl)-quinazoline

Base Information

Chemical Name:2-(p-trifluoromethylphenyl)-4-(2-benzyloxy-naphthalen-1-yl)-quinazoline
CAS No.:1242459-61-5
Molecular Formula:C₃₂H₂₁F₃N₂O
Molecular Weight:506.527
Hs Code.:

Synonyms:2-(p-trifluoromethylphenyl)-4-(2-benzyloxy-naphthalen-1-yl)-quinazoline

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(p-trifluoromethylphenyl)-4-(2-benzyloxy-naphthalen-1-yl)-quinazoline

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Technology Process of 2-(p-trifluoromethylphenyl)-4-(2-benzyloxy-naphthalen-1-yl)-quinazoline

There total 1 articles about 2-(p-trifluoromethylphenyl)-4-(2-benzyloxy-naphthalen-1-yl)-quinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 1041568-57-3
2-(p-trifluoromethylphenyl)-4-chloroquinazoline

: 219834-96-5
2-(phenylmethoxy)-1-naphthalene boronic acid

: 1242459-61-5
2-(p-trifluoromethylphenyl)-4-(2-benzyloxy-naphthalen-1-yl)-quinazoline

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,2-dimethoxyethane; for 24h; Reflux;
DOI:10.1016/j.tetasy.2010.06.012

Reference yield: 92.0%

: 1242459-61-5
2-(p-trifluoromethylphenyl)-4-(2-benzyloxy-naphthalen-1-yl)-quinazoline

: 1242459-63-7
1-(2-(p-trifluoromethylphenyl)-quinazolin-4-yl)-naphthalen-2-ol

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In ethanol; at 20 ℃; for 16h; under 760.051 Torr;
DOI:10.1016/j.tetasy.2010.06.012