methyl 4-S-benzyl-2-deoxy-6-O-(p-tolylsulfonyl)-4-thio-α-D-ribo-hexopyranoside

Base Information

Chemical Name:methyl 4-S-benzyl-2-deoxy-6-O-(p-tolylsulfonyl)-4-thio-α-D-ribo-hexopyranoside
CAS No.:149065-30-5
Molecular Formula:C₂₁H₂₆O₆S₂
Molecular Weight:438.566
Hs Code.:

Synonyms:methyl 4-S-benzyl-2-deoxy-6-O-(p-tolylsulfonyl)-4-thio-α-D-ribo-hexopyranoside

Suppliers and Price of methyl 4-S-benzyl-2-deoxy-6-O-(p-tolylsulfonyl)-4-thio-α-D-ribo-hexopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 4-S-benzyl-2-deoxy-6-O-(p-tolylsulfonyl)-4-thio-α-D-ribo-hexopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 4-S-benzyl-2-deoxy-6-O-(p-tolylsulfonyl)-4-thio-α-D-ribo-hexopyranoside

There total 8 articles about methyl 4-S-benzyl-2-deoxy-6-O-(p-tolylsulfonyl)-4-thio-α-D-ribo-hexopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 149065-28-1
methyl 4-S-benzyl-2-deoxy-4-thio-α-D-ribo-hexopyranoside

: 98-59-9
p-toluenesulfonyl chloride

: 149065-30-5
methyl 4-S-benzyl-2-deoxy-6-O-(p-tolylsulfonyl)-4-thio-α-D-ribo-hexopyranoside

Guidance literature:: With pyridine; In dichloromethane; at 2 ℃; for 144h;

Reference yield:

: 28170-13-0
thiobenzoic acid potassium salt

: 149065-30-5
methyl 4-S-benzyl-2-deoxy-6-O-(p-tolylsulfonyl)-4-thio-α-D-ribo-hexopyranoside

Guidance literature:: Multi-step reaction with 7 steps

1: 74 percent / dimethylformamide; acetonitrile / 16 h / 170 °C

2: 1) Na, 2) Zn, HCl(g) / 1) MeOH, reflux, 16 h, 2) DMF, a) 1.5 h, b) 120 deg C, 30 min

3: 100 percent / pyridine / CH₂Cl₂ / 32 h / Ambient temperature

4: 81 percent / NaOCH₃ / CH₂Cl₂; methanol / 1) 2 deg C, 4 d, 2) rt, 16 h

5: 99 percent / LiAlH₄ / tetrahydrofuran / 2.5 h / Heating

6: 70 percent / AlCl₃/LiAlH₄ / diethyl ether / 4 h / Heating

7: 93 percent / pyridine / CH₂Cl₂ / 144 h / 2 °C

With pyridine; hydrogenchloride; lithium aluminium tetrahydride; aluminium trichloride; sodium methylate; sodium; zinc; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; N,N-dimethyl-formamide; acetonitrile;

Reference yield:

: 4137-34-2
methyl 2,3,6-tri-O-benzoyl-4-O-methylsulphonyl-α-D-galactopyranoside

: 149065-30-5
methyl 4-S-benzyl-2-deoxy-6-O-(p-tolylsulfonyl)-4-thio-α-D-ribo-hexopyranoside

Guidance literature:: Multi-step reaction with 7 steps

1: 74 percent / dimethylformamide; acetonitrile / 16 h / 170 °C

2: 1) Na, 2) Zn, HCl(g) / 1) MeOH, reflux, 16 h, 2) DMF, a) 1.5 h, b) 120 deg C, 30 min

3: 100 percent / pyridine / CH₂Cl₂ / 32 h / Ambient temperature

4: 81 percent / NaOCH₃ / CH₂Cl₂; methanol / 1) 2 deg C, 4 d, 2) rt, 16 h

5: 99 percent / LiAlH₄ / tetrahydrofuran / 2.5 h / Heating

6: 70 percent / AlCl₃/LiAlH₄ / diethyl ether / 4 h / Heating

7: 93 percent / pyridine / CH₂Cl₂ / 144 h / 2 °C

With pyridine; hydrogenchloride; lithium aluminium tetrahydride; aluminium trichloride; sodium methylate; sodium; zinc; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; N,N-dimethyl-formamide; acetonitrile;