1-Methyl-2-(phenylmethyl)-2-piperidinecarboxylic acid ethyl ester

Base Information

Chemical Name:1-Methyl-2-(phenylmethyl)-2-piperidinecarboxylic acid ethyl ester
CAS No.:184033-70-3
Molecular Formula:C₁₆H₂₃NO₂
Molecular Weight:261.364
Hs Code.:
DSSTox Substance ID:DTXSID70441507
Nikkaji Number:J780.205F
Mol file:184033-70-3.mol

Synonyms:1-METHYL-2-(PHENYLMETHYL)-2-PIPERIDINECARBOXYLIC ACID ETHYL ESTER;184033-70-3;DTXSID70441507;AKOS000280565;AKOS040765264;1-Methyl-2-benzyl-2-piperidinecarboxylic acid ethyl ester

Suppliers and Price of 1-Methyl-2-(phenylmethyl)-2-piperidinecarboxylic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

American Custom Chemicals Corporation
1-METHYL-2-(PHENYLMETHYL)-2-PIPERIDINECARBOXYLIC ACID ETHYL ESTER 95.00%
5MG
$ 501.09

Total 0 raw suppliers

Chemical Property of 1-Methyl-2-(phenylmethyl)-2-piperidinecarboxylic acid ethyl ester

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:261.172878976
Heavy Atom Count:19
Complexity:299

Purity/Quality:: 1-METHYL-2-(PHENYLMETHYL)-2-PIPERIDINECARBOXYLIC ACID ETHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C1(CCCCN1C)CC2=CC=CC=C2

Technology Process of 1-Methyl-2-(phenylmethyl)-2-piperidinecarboxylic acid ethyl ester

There total 4 articles about 1-Methyl-2-(phenylmethyl)-2-piperidinecarboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 30727-18-5
ethyl 1-methylpiperidine-2-carboxylate

: 100-39-0
benzyl bromide

: 184033-70-3
2-Benzyl-2-ethoxycarbonyl-1-methylpiperidine

Guidance literature:: With lithium diisopropyl amide; In tetrahydrofuran; hexane; 1.) -78 deg C, 15 min, 2.) -78 deg C to r.t., overnight;

Reference yield:

: 15862-72-3
ethyl pipecolate

: 184033-70-3
2-Benzyl-2-ethoxycarbonyl-1-methylpiperidine

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / H₂ / 10percent Pd/C / aq. acetic acid / 2585.7 Torr / Ambient temperature

2: 92 percent / LDA / tetrahydrofuran; hexane / 1.) -78 deg C, 15 min, 2.) -78 deg C to r.t., overnight

With hydrogen; lithium diisopropyl amide; palladium on activated charcoal; In tetrahydrofuran; hexane; acetic acid;