O,O-dimethyl α-(2,3-dichlorophenoxyacetoxy)-3-nitrobenzylphosphonate

Base Information

• Chemical Name: O,O-dimethyl α-(2,3-dichlorophenoxyacetoxy)-3-nitrobenzylphosphonate
• CAS No.: 904702-58-5
• Molecular Formula: C₁₇H₁₆Cl₂NO₈P
• Molecular Weight: 464.196
• Mol file: 904702-58-5.mol

Synonyms:O,O-dimethyl α-(2,3-dichlorophenoxyacetoxy)-3-nitrobenzylphosphonate

Chemical Property of O,O-dimethyl α-(2,3-dichlorophenoxyacetoxy)-3-nitrobenzylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of O,O-dimethyl α-(2,3-dichlorophenoxyacetoxy)-3-nitrobenzylphosphonate

There total 4 articles about O,O-dimethyl α-(2,3-dichlorophenoxyacetoxy)-3-nitrobenzylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

dimethyl 1-hydroxy-1-(3-nitrophenyl)methylphosphonate (103796-61-8) + (2,3-dichlorophenoxy)acetyl chloride (85630-84-8) → O,O-dimethyl α-(2,3-dichlorophenoxyacetoxy)-3-nitrobenzylphosphonate (904702-58-5)

Guidance literature:

With pyridine; In chloroform; at 10 - 42 ℃;

DOI:10.1021/jf104247w

Reference yield:

2,3-dichlorophenoxyacetic acid (2976-74-1) → O,O-dimethyl α-(2,3-dichlorophenoxyacetoxy)-3-nitrobenzylphosphonate (904702-58-5)

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride

2: pyridine / chloroform / 10 - 42 °C

With pyridine; thionyl chloride; In chloroform;

DOI:10.1021/jf104247w

Reference yield:

2,3-dichlorophenol (576-24-9) → O,O-dimethyl α-(2,3-dichlorophenoxyacetoxy)-3-nitrobenzylphosphonate (904702-58-5)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hydroxide

2: thionyl chloride

3: pyridine / chloroform / 10 - 42 °C

With pyridine; thionyl chloride; sodium hydroxide; In chloroform;

DOI:10.1021/jf104247w

upstream raw materials:

2,3-dichlorophenoxyacetic acid

2,3-dichlorophenol

dimethyl 1-hydroxy-1-(3-nitrophenyl)methylphosphonate

(2,3-dichlorophenoxy)acetyl chloride

Refernces