N-methoxy-3-(methoxymethyl)-N-methylbenzamide

Base Information

• Chemical Name: N-methoxy-3-(methoxymethyl)-N-methylbenzamide
• CAS No.: 199742-78-4
• Molecular Formula: C₁₁H₁₅NO₃
• Molecular Weight: 209.245
• DSSTox Substance ID: DTXSID301251540
• Mol file: 199742-78-4.mol

Synonyms:N-methoxy-3-(methoxymethyl)-N-methylbenzamide;199742-78-4;SCHEMBL1556278;JWVURKJWPUQDEW-UHFFFAOYSA-N;DTXSID301251540;AKOS009129449

Chemical Property of N-methoxy-3-(methoxymethyl)-N-methylbenzamide

Chemical Property:

• XLogP3: 1.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 209.10519334
• Heavy Atom Count: 15
• Complexity: 208

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CN(C(=O)C1=CC=CC(=C1)COC)OC

Technology Process of N-methoxy-3-(methoxymethyl)-N-methylbenzamide

There total 1 articles about N-methoxy-3-(methoxymethyl)-N-methylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

3-methoxymethyl-benzoic acid (32194-76-6) + N,0-dimethylhydroxylamine (1117-97-1) → N-methoxy-3-(methoxymethyl)-N-methylbenzamide (199742-78-4)

Guidance literature:

3-methoxymethyl-benzoic acid; With oxalyl dichloride; N,N-dimethyl-formamide; at 0 - 20 ℃;

N,0-dimethylhydroxylamine; With triethylamine; at 0 - 20 ℃;

Reference yield: 33.0%

1-methyl-1,2,3,4-tetrazole (16681-77-9) + N-methoxy-3-(methoxymethyl)-N-methylbenzamide (199742-78-4) → [3-(methoxymethyl)phenyl](1-methyl-1H-tetrazol-5-yl)methanone (1203575-91-0)

Guidance literature:

1-methyl-1,2,3,4-tetrazole; With isopropylmagnesium chloride; In tetrahydrofuran; at 0 ℃;

N-methoxy-3-(methoxymethyl)-N-methylbenzamide; In tetrahydrofuran; at 5 - 20 ℃;

upstream raw materials:

3-methoxymethyl-benzoic acid

N,0-dimethylhydroxylamine

Downstream raw materials:

[3-(methoxymethyl)phenyl](1-methyl-1H-tetrazol-5-yl)methanone