methyl-N-[2-(1-[benzyl(4-hydroxybutyl)amino]-6-{[(benzyloxy)carbonyl]amino}hexyl)-3-oxa-1-azaspiro[4.5]dec-1-en-4-ylidene]glycinate

Base Information

• Chemical Name: methyl-N-[2-(1-[benzyl(4-hydroxybutyl)amino]-6-{[(benzyloxy)carbonyl]amino}hexyl)-3-oxa-1-azaspiro[4.5]dec-1-en-4-ylidene]glycinate
• CAS No.: 1000886-00-9
• Molecular Formula: C₃₆H₅₀N₄O₆
• Molecular Weight: 634.816
• Mol file: 1000886-00-9.mol

Synonyms:methyl-N-[2-(1-[benzyl(4-hydroxybutyl)amino]-6-{[(benzyloxy)carbonyl]amino}hexyl)-3-oxa-1-azaspiro[4.5]dec-1-en-4-ylidene]glycinate

Chemical Property of methyl-N-[2-(1-[benzyl(4-hydroxybutyl)amino]-6-{[(benzyloxy)carbonyl]amino}hexyl)-3-oxa-1-azaspiro[4.5]dec-1-en-4-ylidene]glycinate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl-N-[2-(1-[benzyl(4-hydroxybutyl)amino]-6-{[(benzyloxy)carbonyl]amino}hexyl)-3-oxa-1-azaspiro[4.5]dec-1-en-4-ylidene]glycinate

There total 1 articles about methyl-N-[2-(1-[benzyl(4-hydroxybutyl)amino]-6-{[(benzyloxy)carbonyl]amino}hexyl)-3-oxa-1-azaspiro[4.5]dec-1-en-4-ylidene]glycinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

methyl 2-(1-isocyanocyclohexanecarboxamido)acetate (1000885-94-8) + 4-(benzylamino)-1-butanol (59578-63-1) + 6-oxo-hexyl-carbamic acid benzyl ester (98648-05-6) → methyl-N-[2-(1-[benzyl(4-hydroxybutyl)amino]-6-{[(benzyloxy)carbonyl]amino}hexyl)-3-oxa-1-azaspiro[4.5]dec-1-en-4-ylidene]glycinate (1000886-00-9)

Guidance literature:

4-(benzylamino)-1-butanol; 6-oxo-hexyl-carbamic acid benzyl ester; In toluene; at 20 ℃; for 0.25h;

methyl 2-(1-isocyanocyclohexanecarboxamido)acetate; With ammonium chloride; In toluene; at 60 ℃; Further stages.;

DOI:10.1021/ol7024372

upstream raw materials:

methyl 2-(1-isocyanocyclohexanecarboxamido)acetate

4-(benzylamino)-1-butanol

6-oxo-hexyl-carbamic acid benzyl ester