7-Benzyloxy-3-(6-benzyloxy-benzo[1,3]dioxol-5-yl)-2H-chromene

Base Information

• Chemical Name: 7-Benzyloxy-3-(6-benzyloxy-benzo[1,3]dioxol-5-yl)-2H-chromene
• CAS No.: 207232-35-7
• Molecular Formula: C₃₀H₂₄O₅
• Molecular Weight: 464.518
• Mol file: 207232-35-7.mol

Synonyms:7-Benzyloxy-3-(6-benzyloxy-benzo[1,3]dioxol-5-yl)-2H-chromene

Chemical Property of 7-Benzyloxy-3-(6-benzyloxy-benzo[1,3]dioxol-5-yl)-2H-chromene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7-Benzyloxy-3-(6-benzyloxy-benzo[1,3]dioxol-5-yl)-2H-chromene

There total 2 articles about 7-Benzyloxy-3-(6-benzyloxy-benzo[1,3]dioxol-5-yl)-2H-chromene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

5-Benzyloxy-2-[(Z)-2-(6-benzyloxy-benzo[1,3]dioxol-5-yl)-3-hydroxy-propenyl]-phenol → 7-Benzyloxy-3-(6-benzyloxy-benzo[1,3]dioxol-5-yl)-2H-chromene (207232-35-7)

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In benzene; for 12h; Ambient temperature;

DOI:10.1016/S0040-4039(98)00299-8

Reference yield:

7-Benzyloxy-3-(6-benzyloxy-benzo[1,3]dioxol-5-yl)-chromen-2-one (207232-32-4) → 7-Benzyloxy-3-(6-benzyloxy-benzo[1,3]dioxol-5-yl)-2H-chromene (207232-35-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / DIBAH / toluene / 0 °C

2: 60 percent / PPh₃, DEAD / benzene / 12 h / Ambient temperature

With diisobutylaluminium hydride; triphenylphosphine; diethylazodicarboxylate; In toluene; benzene;

DOI:10.1016/S0040-4039(98)00299-8

Reference yield: 90.0%

7-Benzyloxy-3-(6-benzyloxy-benzo[1,3]dioxol-5-yl)-2H-chromene (207232-35-7) → (3R,4S)-7-Benzyloxy-3-(6-benzyloxy-benzo[1,3]dioxol-5-yl)-chroman-3,4-diol (207232-36-8)

Guidance literature:

With osmium(VIII) oxide; para-chlorobenzoic acid; dihydroquinine; In dichloromethane; at -78 ℃; for 24h;

DOI:10.1016/S0040-4039(98)00299-8

upstream raw materials:

7-Benzyloxy-3-(6-benzyloxy-benzo[1,3]dioxol-5-yl)-chromen-2-one

Downstream raw materials:

(3R,4S)-7-Benzyloxy-3-(6-benzyloxy-benzo[1,3]dioxol-5-yl)-chroman-3,4-diol

Pisatin

(+)-6a-hydroxymaackiain