(+)-6a-Hydroxymaackiain

Base Information

Chemical Name:(+)-6a-Hydroxymaackiain
CAS No.:14602-93-8
Molecular Formula:C₁₆H₁₂O₆
Molecular Weight:300.268
Hs Code.:
DSSTox Substance ID:DTXSID201141978
Nikkaji Number:J893.901B
Wikidata:Q27120509
Metabolomics Workbench ID:56499

Synonyms:(+)-6a-Hydroxymaackiain;O-demethylpisatin;(+)-O-demethylpisatin;(6AR,12AR)-6H-[1,3]DIOXOLO[5,6][1]BENZOFURO[3,2-C]CHROMENE-3,6A(12AH)-DIOL;6alpha-Hydroxymaackiain;CHEBI:43129;DTXSID201141978;61218-44-8;Q27120509;(6aR,12aR)-6H-[1,3]Dioxolo[5,6]benzofuro[3,2-c][1]benzopyran-3,6a(12aH)-diol;(1R,12R)-5,7,11,19-tetraoxapentacyclo[10.8.0.02,10.04,8.013,18]icosa-2,4(8),9,13(18),14,16-hexaene-1,16-diol;14602-93-8

Suppliers and Price of (+)-6a-Hydroxymaackiain

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of (+)-6a-Hydroxymaackiain

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:0
Exact Mass:300.06338810
Heavy Atom Count:22
Complexity:458

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C2(C(C3=C(O1)C=C(C=C3)O)OC4=CC5=C(C=C42)OCO5)O
Isomeric SMILES:C1[C@]2([C@@H](C3=C(O1)C=C(C=C3)O)OC4=CC5=C(C=C42)OCO5)O

Technology Process of (+)-6a-Hydroxymaackiain

There total 6 articles about (+)-6a-Hydroxymaackiain which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 207232-36-8
(3R,4S)-7-Benzyloxy-3-(6-benzyloxy-benzo[1,3]dioxol-5-yl)-chroman-3,4-diol

: 14602-93-8,61218-44-8
(+)-6a-hydroxymaackiain

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; for 1.5h;
DOI:10.1016/S0040-4039(98)00299-8

Reference yield:

: 5-Benzyloxy-2-[(Z)-2-(6-benzyloxy-benzo[1,3]dioxol-5-yl)-3-hydroxy-propenyl]-phenol

: 14602-93-8,61218-44-8
(+)-6a-hydroxymaackiain

Guidance literature:: Multi-step reaction with 3 steps

1: 60 percent / PPh₃, DEAD / benzene / 12 h / Ambient temperature

2: 90 percent / OsO₄, dihydroquinine, p-chlorobenzoate / CH₂Cl₂ / 24 h / -78 °C

3: 80 percent / hydrogen / 10percent Pd/C / methanol / 1.5 h

With osmium(VIII) oxide; hydrogen; triphenylphosphine; para-chlorobenzoic acid; diethylazodicarboxylate; dihydroquinine; palladium on activated charcoal; In methanol; dichloromethane; benzene;
DOI:10.1016/S0040-4039(98)00299-8

Reference yield:

: 207232-35-7
7-Benzyloxy-3-(6-benzyloxy-benzo[1,3]dioxol-5-yl)-2H-chromene

: 14602-93-8,61218-44-8
(+)-6a-hydroxymaackiain

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / OsO₄, dihydroquinine, p-chlorobenzoate / CH₂Cl₂ / 24 h / -78 °C

2: 80 percent / hydrogen / 10percent Pd/C / methanol / 1.5 h

With osmium(VIII) oxide; hydrogen; para-chlorobenzoic acid; dihydroquinine; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1016/S0040-4039(98)00299-8