Technology Process of C10H15BrO2
There total 11 articles about C10H15BrO2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
methanesulfonamide; potassium carbonate; dihydroquinine 9-O-(9'-phenanthryl) ether; potassium hexacyanoferrate(III);
In
water; tert-butyl alcohol;
at 0 ℃;
enantioselective reaction;
Inert atmosphere;
DOI:10.1002/chem.201404295
- Guidance literature:
-
C19H35BrOSi;
With
K2OsO2*2H2O; 4-[(R)-[(2R,4R,5S)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxy-4-quinolinyl)methoxy]-1-[(R)-[(2R,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxy-4-quinolinyl)methoxy]phthalazine; potassium hexacyanoferrate(III);
at 0 ℃;
for 30h;
With
methanesulfonamide; potassium carbonate;
In
water; tert-butyl alcohol;
DOI:10.1016/j.tetlet.2013.01.115
- Guidance literature:
-
Multi-step reaction with 5 steps
1: neat (no solvent) / Reflux
2: triethylamine / dichloromethane / 20 °C
3: lithium aluminium tetrahydride / tetrahydrofuran / -40 °C
4: 1,8-diazabicyclo[5.4.0]undec-7-ene; dmap / dichloromethane-d2 / 0 - 20 °C
5: K2OsO2*2H2O; potassium hexacyanoferrate(III); 4-[(R)-[(2R,4R,5S)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxy-4-quinolinyl)methoxy]-1-[(R)-[(2R,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxy-4-quinolinyl)methoxy]phthalazine / 30 h / 0 °C
With
dmap; lithium aluminium tetrahydride; K2OsO2*2H2O; 1,8-diazabicyclo[5.4.0]undec-7-ene; 4-[(R)-[(2R,4R,5S)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxy-4-quinolinyl)methoxy]-1-[(R)-[(2R,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxy-4-quinolinyl)methoxy]phthalazine; triethylamine; potassium hexacyanoferrate(III);
In
tetrahydrofuran; dichloromethane; dichloromethane-d2;
1: |Diels-Alder Cycloaddition / 5: |Sharpless Dihydroxylation;
DOI:10.1016/j.tetlet.2013.01.115
