(4,5-dimethoxy-2-nitrophenyl)methyl 4-aminobutanoate monohdrochloride

Base Information

• Chemical Name: (4,5-dimethoxy-2-nitrophenyl)methyl 4-aminobutanoate monohdrochloride
• CAS No.: 123642-56-8
• Molecular Formula: C₁₃H₁₈N₂O₆*ClH
• Molecular Weight: 334.757
• Mol file: 123642-56-8.mol

Synonyms:(4,5-dimethoxy-2-nitrophenyl)methyl 4-aminobutanoate monohdrochloride

Chemical Property of (4,5-dimethoxy-2-nitrophenyl)methyl 4-aminobutanoate monohdrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4,5-dimethoxy-2-nitrophenyl)methyl 4-aminobutanoate monohdrochloride

There total 5 articles about (4,5-dimethoxy-2-nitrophenyl)methyl 4-aminobutanoate monohdrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

(4,5-dimethoxy-2-nitrophenyl)methyl 4butanoate (123642-54-6) → (4,5-dimethoxy-2-nitrophenyl)methyl 4-aminobutanoate monohdrochloride (123642-56-8)

Guidance literature:

With hydrogenchloride; water; In 1,4-dioxane; for 5h;

DOI:10.1039/c1cc15135e

Reference yield:

6-nitroveratryl alcohol (1016-58-6) → (4,5-dimethoxy-2-nitrophenyl)methyl 4-aminobutanoate monohdrochloride (123642-56-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 64.6 percent / PBr₃, pyridine / benzene / 24 h

2: 85 percent / KF / acetone / 16 h / 50 °C

3: 61 percent / 3M HCl / ethyl acetate / 1 h / Ambient temperature

With pyridine; hydrogenchloride; potassium fluoride; phosphorus tribromide; In ethyl acetate; acetone; benzene;

DOI:10.1021/jo00292a038

Reference yield:

6-nitroveratrylbromide (53413-67-5) → (4,5-dimethoxy-2-nitrophenyl)methyl 4-aminobutanoate monohdrochloride (123642-56-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / KF / acetone / 16 h / 50 °C

2: 61 percent / 3M HCl / ethyl acetate / 1 h / Ambient temperature

With hydrogenchloride; potassium fluoride; In ethyl acetate; acetone;

DOI:10.1021/jo00292a038

upstream raw materials:

(4,5-dimethoxy-2-nitrophenyl)methyl 4butanoate

6-nitroveratryl alcohol

6-nitroveratrylbromide

6-nitroveratraldehyde

Downstream raw materials:

4-amino-n-butyric acid