C₃₀H₂₃BF₂N₄O₄

Base Information

• Chemical Name: C₃₀H₂₃BF₂N₄O₄
• CAS No.: 1301766-09-5
• Molecular Formula: C₃₀H₂₃BF₂N₄O₄
• Molecular Weight: 552.345
• Mol file: 1301766-09-5.mol

Synonyms:C₃₀H₂₃BF₂N₄O₄

Chemical Property of C₃₀H₂₃BF₂N₄O₄

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of C₃₀H₂₃BF₂N₄O₄

There total 2 articles about C₃₀H₂₃BF₂N₄O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

C18H15BBr2F2N2 (1301766-06-2) + 4-nitrophenylboronic acid (24067-17-2) → C30H23BF2N4O4 (1301766-09-5)

Guidance literature:

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; caesium carbonate; tri tert-butylphosphoniumtetrafluoroborate; In tetrahydrofuran; water; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1021/ol200799u

Reference yield:

8-mesityl-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (870753-29-0) → C30H23BF2N4O4 (1301766-09-5)

Guidance literature:

Multi-step reaction with 2 steps

1: N-Bromosuccinimide / dichloromethane; N,N-dimethyl-formamide / 2 h / 20 °C

2: tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; caesium carbonate; tri tert-butylphosphoniumtetrafluoroborate / tetrahydrofuran; water / 24 h / 20 °C / Inert atmosphere

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; N-Bromosuccinimide; caesium carbonate; tri tert-butylphosphoniumtetrafluoroborate; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; 2: Suzuki coupling;

DOI:10.1021/ol200799u

Reference yield: 95.0%

C30H23BF2N4O4 (1301766-09-5) → C30H27BF2N4

Guidance literature:

With palladium on activated charcoal; hydrogen; In methanol; at 25 ℃; for 5h;

DOI:10.1039/c3sc53172d

upstream raw materials:

8-mesityl-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene

C₁₈H₁₅BBr₂F₂N₂

4-nitrophenylboronic acid