alpha-(Phenylmethylene)-1H-benzimidazole-2-acetonitrile

Base Information

Chemical Name:alpha-(Phenylmethylene)-1H-benzimidazole-2-acetonitrile
CAS No.:57319-66-1
Molecular Formula:C16H11N3
Molecular Weight:245.283
Hs Code.:2933990090
Nikkaji Number:J2.792.116G
Wikidata:Q76306617
ChEMBL ID:CHEMBL4202629

Synonyms:CHEMBL4202629;57319-66-1;alpha-(Phenylmethylene)-1H-benzimidazole-2-acetonitrile;1H-Benzimidazole-2-acetonitrile, alpha-(phenylmethylene)-;HMS557F12;BDBM50457209;CCG-49250;STK020353;AKOS000431877;NCGC00339868-01;LS-32612;2-(1H-benzimidazol-2-yl)-3-phenylacrylonitrile;AB00083707-01;AB00083707-04;SR-01000638718-1;(2E)-2-(1H-Benzimidazol-2-yl)-3-phenylacrylonitrile;(E)-2-(1H-Benzoimidazole-2-yl)-3-phenylacrylonitrile;(2E)-2-(1H-benzimidazol-2-yl)-3-phenylprop-2-enenitrile;1H-Benzimidazole-2-acetonitrile,.alpha.-(phenylmethylene)-

Suppliers and Price of alpha-(Phenylmethylene)-1H-benzimidazole-2-acetonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of alpha-(Phenylmethylene)-1H-benzimidazole-2-acetonitrile

Chemical Property:

Vapor Pressure:3.01E-09mmHg at 25°C
Boiling Point:476.6°C at 760 mmHg
Flash Point:150.6°C
PSA：52.47000
Density:1.28g/cm³
LogP:3.62708
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:245.095297364
Heavy Atom Count:19
Complexity:386

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C=C(C#N)C2=NC3=CC=CC=C3N2
Isomeric SMILES:C1=CC=C(C=C1)/C=C(\C#N)/C2=NC3=CC=CC=C3N2

Technology Process of alpha-(Phenylmethylene)-1H-benzimidazole-2-acetonitrile

There total 3 articles about alpha-(Phenylmethylene)-1H-benzimidazole-2-acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 4414-88-4
1H-benzimidazol-2-acetonitrile

: 100-52-7
benzaldehyde

: 57319-66-1
2-(1H-benzo[d]imidazol-2-yl)-3-phenylacrylonitrile

Guidance literature:: With mesoporous poly[(perchloric acid functionalized 4-vinylpyridine)-co-(divinylbenzene)-co-(alkene-modified Fe₃O₄ nanoparticles)]; In methanol; at 20 ℃; for 0.5h;
DOI:10.1016/j.mcat.2021.111437

Reference yield:

: 95-54-5
1,2-diamino-benzene

: 57319-66-1
2-(1H-benzo[d]imidazol-2-yl)-3-phenylacrylonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 6 h / Reflux

2: piperidine / ethanol / 1 h / Reflux

With piperidine; In ethanol;
DOI:10.21608/ejchem.2021.87021.4207