Technology Process of (2-formyl-5-methylphenyl) trifluoromethanesulfonate
There total 4 articles about (2-formyl-5-methylphenyl) trifluoromethanesulfonate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
4-methylsalicylaldehyde;
With
triethylamine;
In
dichloromethane;
at 0 - 20 ℃;
for 0.166667h;
Inert atmosphere;
trifluoromethylsulfonic anhydride;
In
dichloromethane;
at 0 - 20 ℃;
Inert atmosphere;
DOI:10.1021/acs.orglett.8b00196
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 3 h / 0 - 20 °C / Inert atmosphere
2.1: n-butyllithium / hexane; diethyl ether / 3 h / 0 - 20 °C / Inert atmosphere
2.2: 0.17 h / 0 °C / Inert atmosphere
2.3: Inert atmosphere
3.1: montmorillonite K-10 / benzene / 24 h / Reflux
4.1: pyridine / dichloromethane / 2.5 h / 0 - 20 °C
With
pyridine; n-butyllithium; sodium hydride;
In
diethyl ether; hexane; dichloromethane; N,N-dimethyl-formamide; mineral oil; benzene;
DOI:10.1021/ja311902f
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: n-butyllithium / hexane; diethyl ether / 3 h / 0 - 20 °C / Inert atmosphere
1.2: 0.17 h / 0 °C / Inert atmosphere
1.3: Inert atmosphere
2.1: montmorillonite K-10 / benzene / 24 h / Reflux
3.1: pyridine / dichloromethane / 2.5 h / 0 - 20 °C
With
pyridine; n-butyllithium;
In
diethyl ether; hexane; dichloromethane; benzene;
DOI:10.1021/ja311902f
