1,1,1-Trifluoro-3-[3-(trifluoromethyl)phenyl]acetone

Base Information

Chemical Name:1,1,1-Trifluoro-3-[3-(trifluoromethyl)phenyl]acetone
CAS No.:161809-65-0
Molecular Formula:C₁₀H₆F₆O
Molecular Weight:256.147
Hs Code.:
DSSTox Substance ID:DTXSID301197362

Synonyms:1,1,1-Trifluoro-3-[3-(trifluoromethyl)phenyl]acetone;161809-65-0;1,1,1-trifluoro-3-[3-(trifluoromethyl)phenyl]propan-2-one;2-Propanone, 1,1,1-trifluoro-3-[3-(trifluoromethyl)phenyl]-;1,1,1-trifluoro-3-(3-(trifluoromethyl)phenyl)propan-2-one;SCHEMBL17961023;NKWDQRUFRMHMKB-UHFFFAOYSA-N;DTXSID301197362;MFCD00098427;AKOS009159344;EN300-1936447;J-009862;1,1,1-Trifluoro-3-(3-trifluoromethyl-phenyl)-propan-2-one;1,1,1-Trifluoro-3-[3-(trifluoromethyl)phenyl]-2-propanone

Suppliers and Price of 1,1,1-Trifluoro-3-[3-(trifluoromethyl)phenyl]acetone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,1,1-Trifluoro-3-[3-(trifluoromethyl)phenyl]acetone

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:256.03228378
Heavy Atom Count:17
Complexity:280

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC(=C1)C(F)(F)F)CC(=O)C(F)(F)F

Technology Process of 1,1,1-Trifluoro-3-[3-(trifluoromethyl)phenyl]acetone

There total 1 articles about 1,1,1-Trifluoro-3-[3-(trifluoromethyl)phenyl]acetone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 383-63-1
ethyl trifluoroacetate,

: 2338-76-3
3-trifluoromethylphenylacetonitrile

: 161809-65-0
3-trifluoromethylbenzyl trifluoromethyl ketone

Guidance literature:: With sodium; In ethanol; for 10h; Heating;
DOI:10.1002/prac.19953370107

Reference yield: 63.0%

: 88284-48-4
2-(trimethylsilyl)phenyl trifluoromethanesulfonate

: 161809-65-0
3-trifluoromethylbenzyl trifluoromethyl ketone

: 1324825-81-1
2,2,2-trifluoro-1-{2-[3-(trifluoromethyl)benzyl]phenyl}ethanone

Guidance literature:: With potassium fluoride; 18-crown-6 ether; In tetrahydrofuran; at 20 ℃; for 48h; Inert atmosphere;
DOI:10.1039/c1cc12820e

Reference yield:

: 161809-65-0
3-trifluoromethylbenzyl trifluoromethyl ketone

: 2-Trifluoromethyl-3-(3-trifluoromethyl-phenyl)-quinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) POCl₃ / 1.) RT, 1 h, 2.) 65 deg C, 6 h

2: 82 percent / acetic acid / 0.5 h / Heating

With trichlorophosphate; In acetic acid;
DOI:10.1002/prac.19953370107