6,9-dibromo-2-(4-fluorophenyl)-1H-phenanthro[9,10-d]imidazole

Base Information

• Chemical Name: 6,9-dibromo-2-(4-fluorophenyl)-1H-phenanthro[9,10-d]imidazole
• CAS No.: 1599476-42-2
• Molecular Formula: C₂₁H₁₁Br₂FN₂
• Molecular Weight: 470.138
• Mol file: 1599476-42-2.mol

Synonyms:6,9-dibromo-2-(4-fluorophenyl)-1H-phenanthro[9,10-d]imidazole

Chemical Property of 6,9-dibromo-2-(4-fluorophenyl)-1H-phenanthro[9,10-d]imidazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6,9-dibromo-2-(4-fluorophenyl)-1H-phenanthro[9,10-d]imidazole

There total 2 articles about 6,9-dibromo-2-(4-fluorophenyl)-1H-phenanthro[9,10-d]imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

4-fluorobenzaldehyde (459-57-4) + 3,6-dibromo-phenanthrene-9,10-dione (53348-05-3) → 6,9-dibromo-2-(4-fluorophenyl)-1H-phenanthro[9,10-d]imidazole (1599476-42-2)

Guidance literature:

With sodium dihydrogenphosphate; ammonium acetate; In ethanol; at 150 ℃; for 6h; Sealed tube;

DOI:10.1021/ja410865z

Reference yield:

9,10-phenanthrenequinone (84-11-7) → 6,9-dibromo-2-(4-fluorophenyl)-1H-phenanthro[9,10-d]imidazole (1599476-42-2)

Guidance literature:

Multi-step reaction with 2 steps

1: dibenzoyl peroxide; bromine / nitrobenzene / 1.5 h / 120 °C

2: ammonium acetate; sodium dihydrogenphosphate / ethanol / 6 h / 150 °C / Sealed tube

With sodium dihydrogenphosphate; ammonium acetate; bromine; dibenzoyl peroxide; In ethanol; nitrobenzene;

DOI:10.1021/ja410865z

Reference yield: 92.0%

6,9-dibromo-2-(4-fluorophenyl)-1H-phenanthro[9,10-d]imidazole (1599476-42-2) + methyl iodide (74-88-4) → 6,9-dibromo-2-(4-fluorophenyl)-1-methylphenanthro[9,10-d]imidazole (1521046-35-4)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;

DOI:10.1021/ja410865z

upstream raw materials:

9,10-phenanthrenequinone

4-fluorobenzaldehyde

3,6-dibromo-phenanthrene-9,10-dione

Downstream raw materials:

6,9-dibromo-2-(4-fluorophenyl)-1-methylphenanthro[9,10-d]imidazole