C₆₅H₇₃N₅O₁₇

Base Information

• Chemical Name: C₆₅H₇₃N₅O₁₇
• CAS No.: 213332-10-6
• Molecular Formula: C₆₅H₇₃N₅O₁₇
• Molecular Weight: 1196.32
• Mol file: 213332-10-6.mol

Synonyms:C₆₅H₇₃N₅O₁₇

Chemical Property of C₆₅H₇₃N₅O₁₇

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₆₅H₇₃N₅O₁₇

There total 6 articles about C₆₅H₇₃N₅O₁₇ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 27.0%

C65H73NO14 (213331-88-5) → C65H73N5O17 (213332-10-6)

Guidance literature:

With sodium azide; ammonium cerium(IV) nitrate; In acetonitrile; at -40 ℃; for 4h;

DOI:10.1021/ja980724z

Reference yield:

2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl-(1->4)-1,5-anhydro-2-deoxy-3,6-di-O-benzyl-D-arabino-hex-1-enitol (114117-12-3) → C65H73N5O17 (213332-10-6)

Guidance literature:

Multi-step reaction with 6 steps

1: 90 percent / I(sym-collidine)2ClO₄, 4A molecular sieves / CH₂Cl₂ / 0.25 h / 0 °C

2: 1.) LiHMDS / 1.) DMF, -40 deg C, 15 min, 2.) DMF, -40 deg C, 4 h

3: 84 percent / di-tert-butylpyridine, MeOTf, 4A molecular sieves / CH₂Cl₂; diethyl ether / 5 h / 0 °C

4: pyridine, DMAP / 0 - 20 °C

5: Na/Hg, aq. Na₂HPO₄ / methanol; ethyl acetate / 2 h / Ambient temperature

6: 27 percent / NaN₃, CAN / acetonitrile / 4 h / -40 °C

With pyridine; dmap; disodium hydrogenphosphate; sodium amalgam; sodium azide; ammonium cerium(IV) nitrate; iodonium(di-γ-collidine) perchlorate; 4 A molecular sieve; Di-tert-butylpyridine; methyl trifluoromethanesulfonate; lithium hexamethyldisilazane; In methanol; diethyl ether; dichloromethane; ethyl acetate; acetonitrile;

DOI:10.1021/ja980724z

Reference yield:

N-[(2S,3S,4S,5R,6R)-4-Benzyloxy-6-benzyloxymethyl-3-iodo-5-((2S,3R,4S,5S,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-2-yl]-benzenesulfonamide → C65H73N5O17 (213332-10-6)

Guidance literature:

Multi-step reaction with 5 steps

1: 1.) LiHMDS / 1.) DMF, -40 deg C, 15 min, 2.) DMF, -40 deg C, 4 h

2: 84 percent / di-tert-butylpyridine, MeOTf, 4A molecular sieves / CH₂Cl₂; diethyl ether / 5 h / 0 °C

3: pyridine, DMAP / 0 - 20 °C

4: Na/Hg, aq. Na₂HPO₄ / methanol; ethyl acetate / 2 h / Ambient temperature

5: 27 percent / NaN₃, CAN / acetonitrile / 4 h / -40 °C

With pyridine; dmap; disodium hydrogenphosphate; sodium amalgam; sodium azide; ammonium cerium(IV) nitrate; 4 A molecular sieve; Di-tert-butylpyridine; methyl trifluoromethanesulfonate; lithium hexamethyldisilazane; In methanol; diethyl ether; dichloromethane; ethyl acetate; acetonitrile;

DOI:10.1021/ja980724z

upstream raw materials:

C₆₅H₇₃NO₁₄

2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl-(1->4)-1,5-anhydro-2-deoxy-3,6-di-O-benzyl-D-arabino-hex-1-enitol

N-[(2S,3R,4R,5S,6R)-4-Benzyloxy-6-benzyloxymethyl-2-ethylsulfanyl-5-((2S,3R,4S,5S,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-3-yl]-benzenesulfonamide

Downstream raw materials:

C₆₇H₇₄Cl₃N₅O₁₅