1-(2-amino-5-benzyloxy-4-methoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-2-methylisoquinoline

Base Information

Chemical Name:1-(2-amino-5-benzyloxy-4-methoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-2-methylisoquinoline
CAS No.:110674-57-2
Molecular Formula:C₂₇H₃₂N₂O₄
Molecular Weight:448.562
Hs Code.:

Synonyms:1-(2-amino-5-benzyloxy-4-methoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-2-methylisoquinoline

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Chemical Property of 1-(2-amino-5-benzyloxy-4-methoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-2-methylisoquinoline

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Technology Process of 1-(2-amino-5-benzyloxy-4-methoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-2-methylisoquinoline

There total 3 articles about 1-(2-amino-5-benzyloxy-4-methoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-2-methylisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 110674-52-7
1-(5-benzyloxy-4-methoxy-2-nitrobenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-2-methylisoquinoline

: 110674-57-2
1-(2-amino-5-benzyloxy-4-methoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-2-methylisoquinoline

Guidance literature:: With zinc; In acetic acid;

Reference yield:

: 110674-46-9
1-(5-benzyloxy-4-methoxy-2-nitrobenzyl)-6,7-dimethoxy-3,4-dihydroisoquinoline methiodide

: 110674-57-2
1-(2-amino-5-benzyloxy-4-methoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-2-methylisoquinoline

Guidance literature:: With hydrogenchloride; acetic acid; zinc;

Reference yield:

: 78792-66-2
1-(5'-benzyloxy-4'-methoxy-2'-nitrobenzyl)-3,4-dihydro-5,6-dimethoxydihydroisoquinoline

: 110674-57-2
1-(2-amino-5-benzyloxy-4-methoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-2-methylisoquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / CHCl₃; benzene / 48 h / Ambient temperature

2: 85 percent / NaBH₄ / methanol / 2 h / Ambient temperature

3: 84 percent / Zn / acetic acid

With sodium tetrahydroborate; zinc; In methanol; chloroform; acetic acid; benzene;