C₄₄H₅₀N₄O₈

Base Information

• Chemical Name: C₄₄H₅₀N₄O₈
• CAS No.: 884871-67-4
• Molecular Formula: C₄₄H₅₀N₄O₈
• Molecular Weight: 762.903
• Mol file: 884871-67-4.mol

Synonyms:C₄₄H₅₀N₄O₈

Chemical Property of C₄₄H₅₀N₄O₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₄H₅₀N₄O₈

There total 6 articles about C₄₄H₅₀N₄O₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-benzyloxymethyl-5-(2,2-dimethyl-[1,3]dioxolan-4-ylmethyl)-4-(1,1-dimethyl-prop-2-ynyl)-1H-imidazole + C22H22N2O5 (884871-65-2) → C44H50N4O8 (884871-67-4)

Guidance literature:

1-benzyloxymethyl-5-(2,2-dimethyl-[1,3]dioxolan-4-ylmethyl)-4-(1,1-dimethyl-prop-2-ynyl)-1H-imidazole; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.25h;

C₂₂H₂₂N₂O₅; In tetrahydrofuran; hexane; at -78 ℃; for 1.5h;

DOI:10.1021/jo060084f

Reference yield:

C17H13ClN2O3 (884871-34-5) → C44H50N4O8 (884871-67-4)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 91 percent / (TMS)3SiH; AIBN / toluene / 100 °C

2.1: 91 percent / DMAP; triethylamine / CH₂Cl₂ / 1 h / 20 °C

3.1: n-BuLi / tetrahydrofuran; hexane / 0.25 h / -78 °C

3.2: 92 percent / tetrahydrofuran; hexane / 1.5 h / -78 °C

With dmap; n-butyllithium; 2,2'-azobis(isobutyronitrile); tris-(trimethylsilyl)silane; triethylamine; In tetrahydrofuran; hexane; dichloromethane; toluene;

DOI:10.1021/jo060084f

Reference yield:

indole-2,3-dione (91-56-5,1186480-61-4,84788-92-1) → C44H50N4O8 (884871-67-4)

Guidance literature:

Multi-step reaction with 5 steps

1.1: 80 percent / acetic acid / ethanol / 1 h / Heating

2.1: 90 percent / triethylamine / CH₂Cl₂ / 20 °C

3.1: 91 percent / (TMS)3SiH; AIBN / toluene / 100 °C

4.1: 91 percent / DMAP; triethylamine / CH₂Cl₂ / 1 h / 20 °C

5.1: n-BuLi / tetrahydrofuran; hexane / 0.25 h / -78 °C

5.2: 92 percent / tetrahydrofuran; hexane / 1.5 h / -78 °C

With dmap; n-butyllithium; 2,2'-azobis(isobutyronitrile); tris-(trimethylsilyl)silane; acetic acid; triethylamine; In tetrahydrofuran; ethanol; hexane; dichloromethane; toluene;

DOI:10.1021/jo060084f

upstream raw materials:

C₂₂H₂₂N₂O₅

C₁₇H₁₃ClN₂O₃

indole-2,3-dione

4-methoxy-aniline

Downstream raw materials:

C₄₀H₄₂N₄O₇

C₃₅H₃₂N₄O₄

C₄₁H₄₆N₄O₈