O-(4-phenyl-2-oxy-1,2,5-oxadiazol-3-yl)methyl carbazate

Base Information

• Chemical Name: O-(4-phenyl-2-oxy-1,2,5-oxadiazol-3-yl)methyl carbazate
• CAS No.: 908255-39-0
• Molecular Formula: C₁₀H₁₀N₄O₄
• Molecular Weight: 250.214
• Mol file: 908255-39-0.mol

Synonyms:O-(4-phenyl-2-oxy-1,2,5-oxadiazol-3-yl)methyl carbazate

Chemical Property of O-(4-phenyl-2-oxy-1,2,5-oxadiazol-3-yl)methyl carbazate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of O-(4-phenyl-2-oxy-1,2,5-oxadiazol-3-yl)methyl carbazate

There total 2 articles about O-(4-phenyl-2-oxy-1,2,5-oxadiazol-3-yl)methyl carbazate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

phenyl (4-phenyl-2-oxy-1,2,5-oxadiazol-3-yl)methyl carbonate (908255-37-8) → O-(4-phenyl-2-oxy-1,2,5-oxadiazol-3-yl)methyl carbazate (908255-39-0)

Guidance literature:

With hydrazine hydrate; In tetrahydrofuran; at 20 ℃;

DOI:10.1002/ardp.200500172

Reference yield:

3-(hydroxymethyl)-4-phenylfuroxan (135733-30-1) → O-(4-phenyl-2-oxy-1,2,5-oxadiazol-3-yl)methyl carbazate (908255-39-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / Et₃N / toluene / 0.75 h / 20 °C

2: 69 percent / hydrazine monohydrate / tetrahydrofuran / 20 °C

With hydrazine hydrate; triethylamine; In tetrahydrofuran; toluene;

DOI:10.1002/ardp.200500172

Reference yield: 50.0%

O-(4-phenyl-2-oxy-1,2,5-oxadiazol-3-yl)methyl carbazate (908255-39-0) + 4-mercaptobenzaldehyde (91358-96-2) → 3-(4-mercaptophenyl-methylidene-hydrazino-carbonyloxymethyl)-4-phenyl-1,2,5-oxadiazol N2-oxide

Guidance literature:

With toluene-4-sulfonic acid; In toluene; at 20 ℃;

DOI:10.1002/ardp.200500172

upstream raw materials:

phenyl (4-phenyl-2-oxy-1,2,5-oxadiazol-3-yl)methyl carbonate

3-(hydroxymethyl)-4-phenylfuroxan