phenyl (4-phenyl-2-oxy-1,2,5-oxadiazol-3-yl)methyl carbonate

Base Information

• Chemical Name: phenyl (4-phenyl-2-oxy-1,2,5-oxadiazol-3-yl)methyl carbonate
• CAS No.: 908255-37-8
• Molecular Formula: C₁₆H₁₂N₂O₅
• Molecular Weight: 312.282
• Mol file: 908255-37-8.mol

Synonyms:phenyl (4-phenyl-2-oxy-1,2,5-oxadiazol-3-yl)methyl carbonate

Chemical Property of phenyl (4-phenyl-2-oxy-1,2,5-oxadiazol-3-yl)methyl carbonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phenyl (4-phenyl-2-oxy-1,2,5-oxadiazol-3-yl)methyl carbonate

There total 1 articles about phenyl (4-phenyl-2-oxy-1,2,5-oxadiazol-3-yl)methyl carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

3-(hydroxymethyl)-4-phenylfuroxan (135733-30-1) + phenyl chloroformate (1885-14-9) → phenyl (4-phenyl-2-oxy-1,2,5-oxadiazol-3-yl)methyl carbonate (908255-37-8)

Guidance literature:

With triethylamine; In toluene; at 20 ℃; for 0.75h;

DOI:10.1002/ardp.200500172

Reference yield: 69.0%

phenyl (4-phenyl-2-oxy-1,2,5-oxadiazol-3-yl)methyl carbonate (908255-37-8) → O-(4-phenyl-2-oxy-1,2,5-oxadiazol-3-yl)methyl carbazate (908255-39-0)

Guidance literature:

With hydrazine hydrate; In tetrahydrofuran; at 20 ℃;

DOI:10.1002/ardp.200500172

Reference yield:

phenyl (4-phenyl-2-oxy-1,2,5-oxadiazol-3-yl)methyl carbonate (908255-37-8) → 3-(4-mercaptophenyl-methylidene-hydrazino-carbonyloxymethyl)-4-phenyl-1,2,5-oxadiazol N2-oxide

Guidance literature:

Multi-step reaction with 2 steps

1: 69 percent / hydrazine monohydrate / tetrahydrofuran / 20 °C

2: 50 percent / p-TsOH / toluene / 20 °C

With toluene-4-sulfonic acid; hydrazine hydrate; In tetrahydrofuran; toluene;

DOI:10.1002/ardp.200500172

upstream raw materials:

3-(hydroxymethyl)-4-phenylfuroxan

phenyl chloroformate

Downstream raw materials:

O-(4-phenyl-2-oxy-1,2,5-oxadiazol-3-yl)methyl carbazate