tert-butyl (3S,4S)-4-{[4-(4-fluorobenzyl)cyclohexyl]amino}tetrahydro-3-furanylcarbamate

Base Information

Chemical Name:tert-butyl (3S,4S)-4-{[4-(4-fluorobenzyl)cyclohexyl]amino}tetrahydro-3-furanylcarbamate
CAS No.:335388-53-9
Molecular Formula:C₂₂H₃₃FN₂O₃
Molecular Weight:392.514
Hs Code.:

Synonyms:tert-butyl (3S,4S)-4-{[4-(4-fluorobenzyl)cyclohexyl]amino}tetrahydro-3-furanylcarbamate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of tert-butyl (3S,4S)-4-{[4-(4-fluorobenzyl)cyclohexyl]amino}tetrahydro-3-furanylcarbamate

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Technology Process of tert-butyl (3S,4S)-4-{[4-(4-fluorobenzyl)cyclohexyl]amino}tetrahydro-3-furanylcarbamate

There total 1 articles about tert-butyl (3S,4S)-4-{[4-(4-fluorobenzyl)cyclohexyl]amino}tetrahydro-3-furanylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 1330763-30-8,1629586-23-7,335276-55-6
(4-aminotetrahydrofuran-3-yl)carbamic acid tert-butyl ester

: 335276-54-5
4-[(4-fluorophenyl)methyl]-cyclohexanone

: 335388-53-9
tert-butyl (3S,4S)-4-{[4-(4-fluorobenzyl)cyclohexyl]amino}tetrahydro-3-furanylcarbamate

: 4248-19-5
tert-butyl carbazate

Guidance literature:: With sodium tris(acetoxy)borohydride; In methanol; dichloromethane; 1,2-dichloro-ethane;

Reference yield: 100.0%

: 335388-53-9
tert-butyl (3S,4S)-4-{[4-(4-fluorobenzyl)cyclohexyl]amino}tetrahydro-3-furanylcarbamate

: (3S,4S)-N₃-[4-(4-fluorobenzyl)cyclohexyl]tetrahydro-3,4-furandiamine dihydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; methanol;

Reference yield:

: 335388-53-9
tert-butyl (3S,4S)-4-{[4-(4-fluorobenzyl)cyclohexyl]amino}tetrahydro-3-furanylcarbamate

: 335388-52-8
N-(3-acetylphenyl)-N'-((3S,4S)-4-{[4-(4-fluorobenzyl)cyclohexyl]amino}tetrahydro-3-furanyl)urea

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / 1,4-dioxane; methanol

2: triethylamine / methanol; dichloromethane; ethyl acetate

With hydrogenchloride; triethylamine; In 1,4-dioxane; methanol; dichloromethane; ethyl acetate;