tert-butyl[(2R,3R)-3-(4-methoxybenzyloxy)-2-methylpent-4-enyloxy]dimethylsilane

Base Information

• Chemical Name: tert-butyl[(2R,3R)-3-(4-methoxybenzyloxy)-2-methylpent-4-enyloxy]dimethylsilane
• CAS No.: 910215-32-6
• Molecular Formula: C₂₀H₃₄O₃Si
• Molecular Weight: 350.574

Synonyms:tert-butyl[(2R,3R)-3-(4-methoxybenzyloxy)-2-methylpent-4-enyloxy]dimethylsilane

Chemical Property of tert-butyl[(2R,3R)-3-(4-methoxybenzyloxy)-2-methylpent-4-enyloxy]dimethylsilane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl[(2R,3R)-3-(4-methoxybenzyloxy)-2-methylpent-4-enyloxy]dimethylsilane

There total 2 articles about tert-butyl[(2R,3R)-3-(4-methoxybenzyloxy)-2-methylpent-4-enyloxy]dimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

(2R,3R)-3-(4-methoxybenzyloxy)-2-methylpent-4-en-1-ol (910215-31-5) + tert-butyldimethylsilyl chloride (18162-48-6) → tert-butyl[(2R,3R)-3-(4-methoxybenzyloxy)-2-methylpent-4-enyloxy]dimethylsilane (910215-32-6)

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; at 20 ℃; for 12h;

DOI:10.1016/j.tetlet.2006.06.082 DOI:10.1055/s-2008-1032028

Reference yield:

(4R,5R)-2-(4-methoxyphenyl)-5-methyl-4-vinyl-1,3-dioxane (910215-30-4) → tert-butyl[(2R,3R)-3-(4-methoxybenzyloxy)-2-methylpent-4-enyloxy]dimethylsilane (910215-32-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / DIBAL-H / CH₂Cl₂ / 2 h / -78 - 0 °C

2: 88 percent / imidazole / dimethylformamide / 12 h / 20 °C

With 1H-imidazole; diisobutylaluminium hydride; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/j.tetlet.2006.06.082

Reference yield: 82.0%

tert-butyl[(2R,3R)-3-(4-methoxybenzyloxy)-2-methylpent-4-enyloxy]dimethylsilane (910215-32-6) → (2S,3R)-4-(tert-butyldimethylsiloxy)-2-(4-methoxybenzyloxy)-3-methylbutyraldehyde (910215-29-1)

Guidance literature:

With 2,6-dimethylpyridine; sodium periodate; osmium(VIII) oxide; In 1,4-dioxane; water; at 20 ℃; for 3h;

DOI:10.1016/j.tetlet.2006.06.082

upstream raw materials:

(2R,3R)-3-(4-methoxybenzyloxy)-2-methylpent-4-en-1-ol

tert-butyldimethylsilyl chloride

(4R,5R)-2-(4-methoxyphenyl)-5-methyl-4-vinyl-1,3-dioxane

Downstream raw materials:

(2S,3R)-4-(tert-butyldimethylsiloxy)-2-(4-methoxybenzyloxy)-3-methylbutyraldehyde

(2S,3S,4S)-4-methoxy-3-(4-methoxybenzyloxy)-2-methylhex-5-enal

(2R,3S,4S)-4-methoxy-3-(4-methoxybenzyloxy)-2-methylhex-5-en-1-ol

(4R,5S,6S)-6-methoxy-5-(4-methoxybenzyloxy)-2,4-dimethylocta-2,7-dien-1-ol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 910215-32-6 tert-butyl[(2R,3R)-3-(4-methoxybenzyloxy)-2-methylpent-4-enyloxy]dimethylsilane

Send

Send

Metric Ton KG G Pound L ML

Send

Send