2-(N-methyl-o-bromoanilino)hept-3-enenitrile

Base Information

• Chemical Name: 2-(N-methyl-o-bromoanilino)hept-3-enenitrile
• CAS No.: 199471-96-0
• Molecular Formula: C₁₄H₁₇BrN₂
• Molecular Weight: 293.206
• Mol file: 199471-96-0.mol

Synonyms:2-(N-methyl-o-bromoanilino)hept-3-enenitrile

Chemical Property of 2-(N-methyl-o-bromoanilino)hept-3-enenitrile

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 2-(N-methyl-o-bromoanilino)hept-3-enenitrile

There total 1 articles about 2-(N-methyl-o-bromoanilino)hept-3-enenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

2-hexenal (505-57-7) + 2-bromo-N-methylaniline (6832-87-7) → 2-(N-methyl-o-bromoanilino)hept-3-enenitrile (199471-96-0)

Guidance literature:

With hydrogenchloride; potassium cyanide; for 12h; Ambient temperature;

DOI:10.1039/a702710i

Reference yield: 60.0%

2-(N-methyl-o-bromoanilino)hept-3-enenitrile (199471-96-0) → 2-methylaminobenzonitrile (17583-40-3)

Guidance literature:

With triethylamine; triphenylphosphine; palladium diacetate; In N,N-dimethyl-formamide; at 100 ℃; for 6h;

DOI:10.1039/a702710i

Reference yield:

2-(N-methyl-o-bromoanilino)hept-3-enenitrile (199471-96-0) → (Z)-2-(N-methyl-o-bromoanilino)hept-2-enenitrile + (E)-2-(N-methyl-o-bromoanilino)hept-2-enenitrile

Guidance literature:

With potassium tert-butylate; In tetrahydrofuran; tert-butyl alcohol; at 0 ℃; for 2h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1039/a702710i

upstream raw materials:

2-hexenal

2-bromo-N-methylaniline

Downstream raw materials:

2-methylaminobenzonitrile

Refernces