(2S,3S)-ethyl 2-hydroxy-3-(N-tosylamino)-4-iodobutyrate

Base Information

Chemical Name:(2S,3S)-ethyl 2-hydroxy-3-(N-tosylamino)-4-iodobutyrate
CAS No.:154701-92-5
Molecular Formula:C₁₃H₁₈INO₅S
Molecular Weight:427.26
Hs Code.:

Synonyms:(2S,3S)-ethyl 2-hydroxy-3-(N-tosylamino)-4-iodobutyrate

Suppliers and Price of (2S,3S)-ethyl 2-hydroxy-3-(N-tosylamino)-4-iodobutyrate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3S)-ethyl 2-hydroxy-3-(N-tosylamino)-4-iodobutyrate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3S)-ethyl 2-hydroxy-3-(N-tosylamino)-4-iodobutyrate

There total 4 articles about (2S,3S)-ethyl 2-hydroxy-3-(N-tosylamino)-4-iodobutyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 154701-91-4
(2S,3R)-2-hydroxy-3-(tosylamino)butano-4-lactone

: 154701-92-5
(2S,3S)-ethyl 2-hydroxy-3-(N-tosylamino)-4-iodobutyrate

Guidance literature:: With trimethylsilyl iodide; In ethanol; dichloromethane; at 25 ℃; for 5h;
DOI:10.1016/S0040-4039(00)60398-2

Reference yield: 88.0%

: 64-17-5
ethanol

: 154701-91-4
(2S,3R)-2-hydroxy-3-(tosylamino)butano-4-lactone

: 154701-92-5
(2S,3S)-ethyl 2-hydroxy-3-(N-tosylamino)-4-iodobutyrate

Guidance literature:: With trimethylsilyl iodide; In dichloromethane; at 20 ℃; for 5.5h;
DOI:10.1002/hlca.19960790426

Reference yield:

: 147228-21-5
(S)-4-<(tolylsulfonyl)amino>-γ-butyrolactone

: 154701-92-5
(2S,3S)-ethyl 2-hydroxy-3-(N-tosylamino)-4-iodobutyrate

Guidance literature:: Multi-step reaction with 2 steps

1: 64 percent / NaHMDS, 3-phenyl-2-(phenylsulfonyl)oxaziridine / tetrahydrofuran / 2 h / -78 °C

2: 88 percent / Me₃SiI / CH₂Cl₂ / 5.5 h / 20 °C

With trimethylsilyl iodide; sodium hexamethyldisilazane; N-(benzenesulfonyl)-3-phenyloxaziridine; In tetrahydrofuran; dichloromethane;
DOI:10.1002/hlca.19960790426