4-NITROPHENYLSUCCINIC ACID

Base Information

• Chemical Name: 4-NITROPHENYLSUCCINIC ACID
• CAS No.: 21021-53-4
• Molecular Formula: C10H9NO6
• Molecular Weight: 239.185
• Hs Code.: 2917399090
• Mol file: 21021-53-4.mol

Synonyms:(4-Nitro-phenyl)-bernsteinsaeure;2-(p-nitrophenyl)succinic acid;4-Nitrophenylsuccinic acid;(4-nitrophenyl)ethane-1,2-dicarboxylic acid;2-(4-Nitrophenyl)succinic acid;p-Nitrophenylsuccinic acid;

Chemical Property of 4-NITROPHENYLSUCCINIC ACID

Chemical Property:

• Vapor Pressure: 2.79E-07mmHg at 25°C
• Melting Point: 216-218oC
• Boiling Point: 404.8°C at 760 mmHg
• Flash Point: 175.9°C
• PSA: 120.42000
• LogP: 1.76090

Purity/Quality:

97% ^*data from raw suppliers

2-(4-NITROPHENYL)SUCCINIC ACID Aldrich ^*data from reagent suppliers

Safty Information:

• Statements: R36/37/38:Irritating to eyes, respiratory system and skin.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36:Wear suitable prot

MSDS Files:

Useful:

Technology Process of 4-NITROPHENYLSUCCINIC ACID

There total 6 articles about 4-NITROPHENYLSUCCINIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

2-phenylsuccinic acid (635-51-8,10424-29-0) → 4-Nitrophenylsuccinic acid (21021-53-4)

Guidance literature:

With nitric acid; at 0 - 20 ℃; for 2h;

DOI:10.1039/c2cc32147e

Reference yield:

2-phenylsuccinic acid (635-51-8,10424-29-0) → 4-Nitrophenylsuccinic acid (21021-53-4) + (2-nitro-phenyl)-succinic acid (6332-94-1)

Guidance literature:

With nitric acid; at 0 ℃;

Reference yield:

*2,3-Dicarbamoyl-3-<4-nitro-phenyl>-propionsaeure-aethylester (91960-25-7) → 4-Nitrophenylsuccinic acid (21021-53-4)

Guidance literature:

With hydrogen bromide; acetic acid;

upstream raw materials:

2-phenylsuccinic acid

*2,3-Dicarbamoyl-3-<4-nitro-phenyl>-propionsaeure-aethylester

nitric acid

Downstream raw materials:

3-(4-nitrophenyl)-2,5-dihydrofuran-2,5-dione

(4-Nitro-phenyl)-bernsteinsaeure-dimethylester

2-(4-Nitro-phenyl)-bernsteinsaeure-monomethylester-⁽⁴⁾

2-(4-aminophenyl)-succinic acid