3E-(methyldiphenylsilyl)-2-propenal

Base Information

• Chemical Name: 3E-(methyldiphenylsilyl)-2-propenal
• CAS No.: 761401-96-1
• Molecular Formula: C₁₆H₁₆OSi
• Molecular Weight: 252.388
• Mol file: 761401-96-1.mol

Synonyms:3E-(methyldiphenylsilyl)-2-propenal

Chemical Property of 3E-(methyldiphenylsilyl)-2-propenal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3E-(methyldiphenylsilyl)-2-propenal

There total 2 articles about 3E-(methyldiphenylsilyl)-2-propenal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

3E-(methyldiphenylsilyl)-2-propen-1-ol (101844-25-1) → 3E-(methyldiphenylsilyl)-2-propenal (761401-96-1)

Guidance literature:

With manganese(IV) oxide; In dichloromethane; for 3h; Heating;

DOI:10.1016/j.tet.2004.05.115

Reference yield:

chloromethyldiphenylsilane (144-79-6) → 3E-(methyldiphenylsilyl)-2-propenal (761401-96-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: MeMgBr / diethyl ether; tetrahydrofuran / 0 - 4 °C

1.2: 95 percent / diethyl ether; tetrahydrofuran / 2 h / 40 °C

2.1: 99 percent / Red-Al(R) / diethyl ether; toluene / 2 h / 0 - 20 °C

3.1: 85 percent / MnO₂ / CH₂Cl₂ / 3 h / Heating

With manganese(IV) oxide; methylmagnesium bromide; sodium bis(2-methoxyethoxy)aluminium dihydride; In tetrahydrofuran; diethyl ether; dichloromethane; toluene;

DOI:10.1016/j.tet.2004.05.115

Reference yield:

hex-5-en-1-amine (34825-70-2) + 3E-(methyldiphenylsilyl)-2-propenal (761401-96-1) → Hex-5-enyl-[(E)-3-(methyl-diphenyl-silanyl)-prop-2-en-(Z)-ylidene]-amine

Guidance literature:

In methanol; at 20 ℃; for 2h;

DOI:10.1016/j.tet.2004.05.115

upstream raw materials:

3E-(methyldiphenylsilyl)-2-propen-1-ol

chloromethyldiphenylsilane

Downstream raw materials:

1-[(E)-3-(Methyl-diphenyl-silanyl)-allyl]-piperidin-2-one

But-3-enoic acid allyl-[(E)-3-(methyl-diphenyl-silanyl)-allyl]-amide

Pent-4-enoic acid allyl-[(E)-3-(methyl-diphenyl-silanyl)-allyl]-amide

{1-[3-(methyl-diphenyl-silanyl)-allyl]-2-oxo-2,3,4,7-tetrahydro-1H-azepin-3-yl}-carbamic acid tert-butyl ester