Pent-4-enoic acid allyl-[(E)-3-(methyl-diphenyl-silanyl)-allyl]-amide

Base Information

• Chemical Name: Pent-4-enoic acid allyl-[(E)-3-(methyl-diphenyl-silanyl)-allyl]-amide
• CAS No.: 761402-00-0
• Molecular Formula: C₂₄H₂₉NOSi
• Molecular Weight: 375.586
• Mol file: 761402-00-0.mol

Synonyms:Pent-4-enoic acid allyl-[(E)-3-(methyl-diphenyl-silanyl)-allyl]-amide

Chemical Property of Pent-4-enoic acid allyl-[(E)-3-(methyl-diphenyl-silanyl)-allyl]-amide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of Pent-4-enoic acid allyl-[(E)-3-(methyl-diphenyl-silanyl)-allyl]-amide

There total 5 articles about Pent-4-enoic acid allyl-[(E)-3-(methyl-diphenyl-silanyl)-allyl]-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

pent-4-enoyl chloride (39716-58-0) + Allyl-[(E)-3-(methyl-diphenyl-silanyl)-allyl]-amine (761401-97-2) → Pent-4-enoic acid allyl-[(E)-3-(methyl-diphenyl-silanyl)-allyl]-amide (761402-00-0)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 25 ℃; for 4.5h;

DOI:10.1016/j.tet.2004.05.115

Reference yield:

chloromethyldiphenylsilane (144-79-6) → Pent-4-enoic acid allyl-[(E)-3-(methyl-diphenyl-silanyl)-allyl]-amide (761402-00-0)

Guidance literature:

Multi-step reaction with 6 steps

1.1: MeMgBr / diethyl ether; tetrahydrofuran / 0 - 4 °C

1.2: 95 percent / diethyl ether; tetrahydrofuran / 2 h / 40 °C

2.1: 99 percent / Red-Al(R) / diethyl ether; toluene / 2 h / 0 - 20 °C

3.1: 85 percent / MnO₂ / CH₂Cl₂ / 3 h / Heating

4.1: methanol / 2 h / 20 °C

5.1: NaBH₄ / methanol / 18 h / 20 °C

6.1: 81 percent / Et₃N / CH₂Cl₂ / 4.5 h / 0 - 25 °C

With manganese(IV) oxide; sodium tetrahydroborate; methylmagnesium bromide; triethylamine; sodium bis(2-methoxyethoxy)aluminium dihydride; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; toluene;

DOI:10.1016/j.tet.2004.05.115

Reference yield:

3E-(methyldiphenylsilyl)-2-propen-1-ol (101844-25-1) → Pent-4-enoic acid allyl-[(E)-3-(methyl-diphenyl-silanyl)-allyl]-amide (761402-00-0)

Guidance literature:

Multi-step reaction with 4 steps

1: 85 percent / MnO₂ / CH₂Cl₂ / 3 h / Heating

2: methanol / 2 h / 20 °C

3: NaBH₄ / methanol / 18 h / 20 °C

4: 81 percent / Et₃N / CH₂Cl₂ / 4.5 h / 0 - 25 °C

With manganese(IV) oxide; sodium tetrahydroborate; triethylamine; In methanol; dichloromethane;

DOI:10.1016/j.tet.2004.05.115

upstream raw materials:

pent-4-enoyl chloride

Allyl-[(E)-3-(methyl-diphenyl-silanyl)-allyl]-amine

chloromethyldiphenylsilane

3E-(methyldiphenylsilyl)-2-propen-1-ol

Downstream raw materials:

1-[(E)-3-(Methyl-diphenyl-silanyl)-allyl]-1,3,4,7-tetrahydro-azepin-2-one