dibenzyl-1,3 thymine

Base Information

• Chemical Name: dibenzyl-1,3 thymine
• CAS No.: 78450-19-8
• Molecular Formula: C₁₉H₁₈N₂O₂
• Molecular Weight: 306.364
• Mol file: 78450-19-8.mol

Synonyms:dibenzyl-1,3 thymine

Chemical Property of dibenzyl-1,3 thymine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of dibenzyl-1,3 thymine

There total 4 articles about dibenzyl-1,3 thymine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

benzyl bromide (100-39-0) + thymin (65-71-4,28806-14-6,691841-57-3) → dibenzyl-1,3 thymine (78450-19-8)

Guidance literature:

thymin; With potassium carbonate; for 1h; Milling;

benzyl bromide; In N,N-dimethyl-formamide; for 1h; Milling;

DOI:10.3762/bjoc.13.169

Reference yield: 97.0%

benzyl chloride (100-44-7) + thymin (65-71-4,28806-14-6,691841-57-3) → dibenzyl-1,3 thymine (78450-19-8)

Guidance literature:

With tetrabutyl ammonium fluoride; for 8h;

DOI:10.1080/00397919108055451

Reference yield: 29.0%

1,3-dibenzyl-5-methylenehexahydropyrimidine-2,4-dione (183367-33-1) → dibenzyl-1,3 thymine (78450-19-8)

Guidance literature:

With hydrogen; platinum(IV) oxide;

DOI:10.1002/jhet.5570330444

upstream raw materials:

benzyl bromide

thymin

benzyl chloride

1,3-dibenzyl-5-methylenehexahydropyrimidine-2,4-dione

Downstream raw materials:

3-benzyl-5-methyl-2,4(1H)-pyrimidinedione

thymin