N₆-(2-isopropoxy-5-methyl-4-(1-methylpiperidin-4-yl)phenyl)-N₄-(2-(isopropylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine

Base Information

• Chemical Name: N₆-(2-isopropoxy-5-methyl-4-(1-methylpiperidin-4-yl)phenyl)-N₄-(2-(isopropylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
• CAS No.: 1032902-80-9
• Molecular Formula: C₃₀H₃₉N₇O₃S
• Molecular Weight: 577.751

Synonyms:N₆-(2-isopropoxy-5-methyl-4-(1-methylpiperidin-4-yl)phenyl)-N₄-(2-(isopropylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine

Chemical Property of N₆-(2-isopropoxy-5-methyl-4-(1-methylpiperidin-4-yl)phenyl)-N₄-(2-(isopropylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N₆-(2-isopropoxy-5-methyl-4-(1-methylpiperidin-4-yl)phenyl)-N₄-(2-(isopropylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine

There total 3 articles about N₆-(2-isopropoxy-5-methyl-4-(1-methylpiperidin-4-yl)phenyl)-N₄-(2-(isopropylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-amino-2-(isopropylsulphonyl)benzene (76697-50-2) → N6-(2-isopropoxy-5-methyl-4-(1-methylpiperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine (1032902-80-9)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrogenchloride / water; isopropyl alcohol / 150 °C / Microwave irradiation

2: hydrogenchloride / water; isopropyl alcohol / 0.5 h / 160 °C / Microwave irradiation

3: triethylamine / N,N-dimethyl-formamide / 0.17 h / 100 °C / Microwave irradiation

With hydrogenchloride; triethylamine; In water; N,N-dimethyl-formamide; isopropyl alcohol;

DOI:10.1016/j.bmcl.2015.11.049

Reference yield:

C29H37N7O3S (1032902-77-4) + methyl iodide (74-88-4) → N6-(2-isopropoxy-5-methyl-4-(1-methylpiperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine (1032902-80-9)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; at 100 ℃; for 0.166667h; Microwave irradiation;

DOI:10.1016/j.bmcl.2015.11.049

Reference yield:

4,6-dichloro-1H-pyrazolo[3,4-d]pyrimidine (42754-96-1) → N6-(2-isopropoxy-5-methyl-4-(1-methylpiperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine (1032902-80-9)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrogenchloride / water; isopropyl alcohol / 150 °C / Microwave irradiation

2: hydrogenchloride / water; isopropyl alcohol / 0.5 h / 160 °C / Microwave irradiation

3: triethylamine / N,N-dimethyl-formamide / 0.17 h / 100 °C / Microwave irradiation

With hydrogenchloride; triethylamine; In water; N,N-dimethyl-formamide; isopropyl alcohol;

DOI:10.1016/j.bmcl.2015.11.049

upstream raw materials:

4,6-dichloro-1H-pyrazolo[3,4-d]pyrimidine

1-amino-2-(isopropylsulphonyl)benzene

C₂₉H₃₇N₇O₃S

methyl iodide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1032902-80-9 N₆-(2-isopropoxy-5-methyl-4-(1-methylpiperidin-4-yl)phenyl)-N₄-(2-(isopropylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine

Send

Send

Metric Ton KG G Pound L ML

Send

Send