Pyroglutamylbenzylamide

Base Information

Chemical Name:Pyroglutamylbenzylamide
CAS No.:87766-32-3
Molecular Formula:C12H14 N2 O2
Molecular Weight:218.255
Hs Code.:
DSSTox Substance ID:DTXSID60236621
Nikkaji Number:J261.793E
Wikidata:Q83118595
ChEMBL ID:CHEMBL4633140
Mol file:87766-32-3.mol

Synonyms:pyroglutamyl benzylamide;pyroglutamylbenzylamide

Suppliers and Price of Pyroglutamylbenzylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Pyroglutamylbenzylamide

Chemical Property:

Vapor Pressure:2.34E-12mmHg at 25°C
Boiling Point:555°C at 760 mmHg
Flash Point:244.6°C
PSA：58.20000
Density:1.199g/cm³
LogP:1.30110
XLogP3:0.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:218.105527694
Heavy Atom Count:16
Complexity:272

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)NC1C(=O)NCC2=CC=CC=C2
Isomeric SMILES:C1CC(=O)N[C@@H]1C(=O)NCC2=CC=CC=C2

Technology Process of Pyroglutamylbenzylamide

There total 7 articles about Pyroglutamylbenzylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 100-46-9
benzylamine

: 511543-55-8
(2R,5S)-2-trichloromethyl-1-aza-3-oxabicyclo[3.3.0]octane-4,8-dione

: 87766-32-3
(2S)-5-oxopyrrolidine-2-carboxylic acid benzylamide

Guidance literature:: In toluene; for 2h; Heating;
DOI:10.1016/j.tetasy.2007.07.012

Reference yield: 93.0%

: 100-46-9
benzylamine

: 14842-41-2
(S,S)-1,7-diazatricyclo[7.3.0.0^7,11]dodecane-2,6,8,12-tetrone

: 87766-32-3
(2S)-5-oxopyrrolidine-2-carboxylic acid benzylamide

: (2S,5S)-N,N'-dibenzyl-3,6-dioxo-2,5-piperazinedipropanamide

Guidance literature:: In N,N-dimethyl-formamide; at 25 ℃;
DOI:10.1021/jo0160928

Reference yield: 91.0%

: 56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6
L-glutamic acid

: 100-46-9
benzylamine

: 87766-32-3
(2S)-5-oxopyrrolidine-2-carboxylic acid benzylamide

Guidance literature:: With tris(2,2,2-trifluoroethyl) borate; for 24h; chemoselective reaction; Reflux; Dean-Stark; Green chemistry;
DOI:10.1002/chem.201800372