1,2-diisocyanobenzene

Base Information

• Chemical Name: 1,2-diisocyanobenzene
• CAS No.: 94217-36-4
• Molecular Formula: C₈H₄N₂
• Molecular Weight: 128.133
• Mol file: 94217-36-4.mol

Synonyms:1,2-diisocyanobenzene

Chemical Property of 1,2-diisocyanobenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-diisocyanobenzene

There total 2 articles about 1,2-diisocyanobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

N,N'-benzene-1,2-diyldiformamide (31354-51-5) → 1,2-diisocyanobenzene (94217-36-4)

Guidance literature:

With triethylamine; trichloromethyl chloroformate; In dichloromethane; at -78 - 0 ℃;

DOI:10.1055/s-1988-27683

Reference yield:

1,2-diamino-benzene (95-54-5) + formyl acetic anhydride (2258-42-6) → 1,2-diisocyanobenzene (94217-36-4)

Guidance literature:

1,2-diamino-benzene; formyl acetic anhydride; In dichloromethane; at 0 - 20 ℃;

With trimethylamine; trichlorophosphate; In dichloromethane; at 0 ℃; for 2h;

DOI:10.1021/acs.joc.0c00647

Reference yield: 95.0%

Bisphosphine oxide (71360-04-8) + 1,2-diisocyanobenzene (94217-36-4) → bis(2-methoxyphenyl)(quinoxalin-2-yl)phosphine oxide

Guidance literature:

With silver nitrate; In acetonitrile; at 80 ℃; for 12h;

DOI:10.1021/acs.joc.8b01657

upstream raw materials:

N,N'-benzene-1,2-diyldiformamide

1,2-diamino-benzene

formyl acetic anhydride

Downstream raw materials:

[(silver(I))(1,2-phenylenediisocyanide)]n(BF₄)n

Refernces

• 1、 Leifert, Dirk,Studer, Armido. "Iodinated (Perfluoro)alkyl Quinoxalines by Atom Transfer Radical Addition Using ortho-Diisocyanoarenes as Radical Acceptors". supporting information. p. 11660 - 11663. Retrieved 2016/10/24.