Technology Process of C14H20O
There total 1 articles about C14H20O which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride;
In
toluene;
for 12h;
Reflux;
Inert atmosphere;
DOI:10.1021/ol302309c
- Guidance literature:
-
C14H20O;
With
osmium(VIII) oxide; 4-methylmorpholine N-oxide;
In
tetrahydrofuran; water; tert-butyl alcohol;
for 12h;
Inert atmosphere;
With
sodium periodate;
In
methanol; water;
at 0 - 20 ℃;
for 3h;
Inert atmosphere;
DOI:10.1021/ol302309c
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 4-methylmorpholine N-oxide; osmium(VIII) oxide / tert-butyl alcohol; water; tetrahydrofuran / 12 h / Inert atmosphere
1.2: 3 h / 0 - 20 °C / Inert atmosphere
2.1: di-n-butylboryl trifluoromethanesulfonate / dichloromethane / 0.17 h / 0 °C / Inert atmosphere
2.2: 1 h / 0 °C / Inert atmosphere
2.3: 6 h / -78 - 0 °C / Inert atmosphere
3.1: 2,6-dimethylpyridine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere
4.1: sodium tetrahydroborate / water; tetrahydrofuran / 0 - 20 °C / Inert atmosphere
5.1: triethylamine; dmap / dichloromethane / 0 - 20 °C / Inert atmosphere
6.1: copper dichloride; 1-Phenylprop-1-yne / tetrahydrofuran / 24 h / Inert atmosphere; Reflux
With
2,6-dimethylpyridine; 1-Phenylprop-1-yne; dmap; sodium tetrahydroborate; osmium(VIII) oxide; di-n-butylboryl trifluoromethanesulfonate; 4-methylmorpholine N-oxide; triethylamine; copper dichloride;
In
tetrahydrofuran; dichloromethane; water; tert-butyl alcohol;
2.1: |Evans Aldol Reaction / 2.2: |Evans Aldol Reaction / 2.3: |Evans Aldol Reaction;
DOI:10.1021/ol302309c
