(1R,2R)-2-(2-bromophenyl)-N-(1-cyanocyclopropyl)-5,5-difluorocyclohexanecarboxamide

Base Information

Chemical Name:(1R,2R)-2-(2-bromophenyl)-N-(1-cyanocyclopropyl)-5,5-difluorocyclohexanecarboxamide
CAS No.:819858-52-1
Molecular Formula:C₁₇H₁₇BrF₂N₂O
Molecular Weight:383.236
Hs Code.:

Synonyms:(1R,2R)-2-(2-bromophenyl)-N-(1-cyanocyclopropyl)-5,5-difluorocyclohexanecarboxamide

Suppliers and Price of (1R,2R)-2-(2-bromophenyl)-N-(1-cyanocyclopropyl)-5,5-difluorocyclohexanecarboxamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1R,2R)-2-(2-bromophenyl)-N-(1-cyanocyclopropyl)-5,5-difluorocyclohexanecarboxamide

Chemical Property:

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Technology Process of (1R,2R)-2-(2-bromophenyl)-N-(1-cyanocyclopropyl)-5,5-difluorocyclohexanecarboxamide

There total 1 articles about (1R,2R)-2-(2-bromophenyl)-N-(1-cyanocyclopropyl)-5,5-difluorocyclohexanecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 819858-50-9
(1R,2R)-2-(2-bromophenyl)-5,5-difluorocyclohexanecarboxylic acid

: 127946-77-4
1-amino-1-cyclopropanecarbonitrile hydrochloride

: 819858-52-1
(1R,2R)-2-(2-bromophenyl)-N-(1-cyanocyclopropyl)-5,5-difluorocyclohexanecarboxamide

Guidance literature:: With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; triethylamine; In DMF (N,N-dimethyl-formamide); at 0 - 20 ℃; for 2.5h;

Reference yield:

: 819858-52-1
(1R,2R)-2-(2-bromophenyl)-N-(1-cyanocyclopropyl)-5,5-difluorocyclohexanecarboxamide

: 98546-51-1
(4-thiomethoxyphenyl)boronic acid

: (1R,2R)-N-(1-cyanocyclopropyl)-5,5-difluoro-2-[4'-(methylthio)-1,1'-biphenyl-2-yl]cyclohexanecarboxamide

Guidance literature:: With sodium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In DMF (N,N-dimethyl-formamide); water; at 85 ℃; for 17h;