2-Keto-3-deoxy-6-phosphogluconate

Base Information

• Chemical Name: 2-Keto-3-deoxy-6-phosphogluconate
• CAS No.: 27244-54-8
• Molecular Formula: C6H11 O9 P
• Molecular Weight: 258.122
• Hs Code.: 2931900090
• Nikkaji Number: J40.082C
• Wikidata: Q27098301
• Metabolomics Workbench ID: 37761
• ChEMBL ID: CHEMBL1162150
• Mol file: 27244-54-8.mol

Synonyms:2-keto-3-deoxy-6-phosphogluconate;3-deoxy-D-erythro-hex-2-ulosonic acid 6-phosphate;KDPG intermediate

Chemical Property of 2-Keto-3-deoxy-6-phosphogluconate

Chemical Property:

• Vapor Pressure: 1.18E-17mmHg at 25°C
• Boiling Point: 614.2°Cat760mmHg
• Flash Point: 325.3°C
• PSA: 171.40000
• Density: 1.835g/cm³
• LogP: -2.13870
• Storage Temp.: -20°C
• XLogP3: -3.4
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 7
• Exact Mass: 258.01406892
• Heavy Atom Count: 16
• Complexity: 307

Purity/Quality:

94% ^*data from raw suppliers

3-Deoxy-2-keto-6-phosphogluconic acid lithium salt ≥95% (TLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C(COP(=O)(O)O)O)O)C(=O)C(=O)O
• Isomeric SMILES: C([C@@H]([C@@H](COP(=O)(O)O)O)O)C(=O)C(=O)O

Technology Process of 2-Keto-3-deoxy-6-phosphogluconate

There total 1 articles about 2-Keto-3-deoxy-6-phosphogluconate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

D-glyceraldehyde-3-phosphate (591-57-1) + 2-oxo-propionic acid (127-17-3) → 3-deoxy-D-erythro-hex-2-ulosonic acid 6-phosphate (27244-54-8)

Guidance literature:

In water; at 30 ℃; Alcaligenes eutrophus H₁₆ F₃₄;

DOI:10.1016/0008-6215(93)80029-E

Reference yield:

3-deoxy-D-erythro-hex-2-ulosonic acid 6-phosphate (27244-54-8) → 2-oxo-propionic acid (127-17-3)

Guidance literature:

With Saccharophagus degradans 2-40^T 2-keto-3-deoxy-phosphogluconate aldolase; In aq. buffer; at 30 ℃; for 1h; Enzymatic reaction;

DOI:10.1016/j.procbio.2016.07.020

Reference yield:

3-deoxy-D-erythro-hex-2-ulosonic acid 6-phosphate (27244-54-8) → D-glyceraldehyde-3-phosphate (591-57-1) + 2-oxo-propionic acid (127-17-3)

Guidance literature:

With Escherichia coli 2-keto-3-deoxy-6-phosphogluconate aldolase; triethanolamine buffer; at 25 ℃; pH=7.6; Enzyme kinetics;

DOI:10.1016/j.bmc.2004.03.039

upstream raw materials:

D-glyceraldehyde-3-phosphate

2-oxo-propionic acid

Downstream raw materials:

D-glyceraldehyde-3-phosphate

2-oxo-propionic acid