[2-cyano-3-(2-fluoro-phenyl)-3-hydroxy-propylamino]-acetic acid methyl ester

Base Information

Chemical Name:[2-cyano-3-(2-fluoro-phenyl)-3-hydroxy-propylamino]-acetic acid methyl ester
CAS No.:951380-58-8
Molecular Formula:C₁₃H₁₅FN₂O₃
Molecular Weight:266.272
Hs Code.:

Synonyms:[2-cyano-3-(2-fluoro-phenyl)-3-hydroxy-propylamino]-acetic acid methyl ester

Suppliers and Price of [2-cyano-3-(2-fluoro-phenyl)-3-hydroxy-propylamino]-acetic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of [2-cyano-3-(2-fluoro-phenyl)-3-hydroxy-propylamino]-acetic acid methyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Technology Process of [2-cyano-3-(2-fluoro-phenyl)-3-hydroxy-propylamino]-acetic acid methyl ester

There total 1 articles about [2-cyano-3-(2-fluoro-phenyl)-3-hydroxy-propylamino]-acetic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 5680-79-5,883886-67-7
glycine ethyl ester hydrochloride

: 220175-92-8
(RS)-2-((2-fluorophenyl)(hydroxy)methyl)acrylonitrile

: 951380-58-8
[2-cyano-3-(2-fluoro-phenyl)-3-hydroxy-propylamino]-acetic acid methyl ester

Guidance literature:: With triethylamine; In methanol; for 12h; Heating;
DOI:10.1016/j.tet.2007.06.115

Reference yield:

: 951380-58-8
[2-cyano-3-(2-fluoro-phenyl)-3-hydroxy-propylamino]-acetic acid methyl ester

: C₁₃H₁₉N₂O₃F

Guidance literature:: With hydrogen; nickel; In methanol; at 20 ℃; for 3h; under 2068.65 Torr;
DOI:10.1016/j.tet.2007.06.115

Reference yield:

: 951380-58-8
[2-cyano-3-(2-fluoro-phenyl)-3-hydroxy-propylamino]-acetic acid methyl ester

: 6-[(2-fluoro-phenyl)-hydroxy-methyl]-5,6,7,8-tetrahydro-imidazo[1,2-a]pyrimidin-2-one hydrobromide

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Raney-Ni / methanol / 3 h / 20 °C / 2068.65 Torr

2: ethanol / 8 h / Heating

With hydrogen; nickel; In methanol; ethanol;
DOI:10.1016/j.tet.2007.06.115