Technology Process of <2-(2,2-Dimethylpropyl)phenyl>diazomethane
There total 5 articles about <2-(2,2-Dimethylpropyl)phenyl>diazomethane which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium hydroxide;
In
1,4-dioxane;
at 80 ℃;
for 0.5h;
Yield given;
DOI:10.1021/jo00093a014
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) aq. NaOH, 2.) H2, sodium hydrogen phosphate, H3PO4 / 2.) 10percent Pd/C / 1.) 95 deg C, 45 min, 2.) 120 deg C, 2.8 atm, 14 h
2: 86 percent / LiAlH4 / diethyl ether / 5 h / Heating
3: 81 percent / CrO3-pyridine / acetic acid; diethyl ether / 0.25 h / 5 °C
4: 84 percent / methanol / 14 h / Ambient temperature
5: 50percent aq. NaOH / dioxane / 0.5 h / 80 °C
With
sodium hydroxide; disodium hydrogenphosphate; lithium aluminium tetrahydride; phosphoric acid; chromium trioxide-pyridine complex; hydrogen;
palladium on activated charcoal;
In
1,4-dioxane; methanol; diethyl ether; acetic acid;
DOI:10.1021/jo00093a014
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 86 percent / LiAlH4 / diethyl ether / 5 h / Heating
2: 81 percent / CrO3-pyridine / acetic acid; diethyl ether / 0.25 h / 5 °C
3: 84 percent / methanol / 14 h / Ambient temperature
4: 50percent aq. NaOH / dioxane / 0.5 h / 80 °C
With
sodium hydroxide; lithium aluminium tetrahydride; chromium trioxide-pyridine complex;
In
1,4-dioxane; methanol; diethyl ether; acetic acid;
DOI:10.1021/jo00093a014
