5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(tert-butyldimethylsilyl)-(-)-5-iodouridine

Base Information

Chemical Name:5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(tert-butyldimethylsilyl)-(-)-5-iodouridine
CAS No.:158728-70-2
Molecular Formula:C₃₆H₄₃IN₂O₈Si
Molecular Weight:786.736
Hs Code.:

Synonyms:5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(tert-butyldimethylsilyl)-(-)-5-iodouridine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(tert-butyldimethylsilyl)-(-)-5-iodouridine

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Technology Process of 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(tert-butyldimethylsilyl)-(-)-5-iodouridine

There total 6 articles about 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(tert-butyldimethylsilyl)-(-)-5-iodouridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 18162-48-6
tert-butyldimethylsilyl chloride

: 158728-68-8
5′-O-(4,4′-dimethyltrityl)-5-iodouridine

: 158728-70-2
5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(tert-butyldimethylsilyl)-(-)-5-iodouridine

Guidance literature:: 5′-O-(4,4′-dimethyltrityl)-5-iodouridine; With pyridine; silver nitrate; In tetrahydrofuran; at 20 ℃; for 0.25h;

tert-butyldimethylsilyl chloride; In tetrahydrofuran; at 20 ℃; for 2h;
DOI:10.1039/b816768k