nitromethyl phenylethynyl ketone

Base Information

• Chemical Name: nitromethyl phenylethynyl ketone
• CAS No.: 116043-21-1
• Molecular Formula: C₁₀H₇NO₃
• Molecular Weight: 189.17
• Mol file: 116043-21-1.mol

Synonyms:nitromethyl phenylethynyl ketone

Chemical Property of nitromethyl phenylethynyl ketone

Chemical Property:

Purity/Quality:

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MSDS Files:

Useful:

Technology Process of nitromethyl phenylethynyl ketone

There total 2 articles about nitromethyl phenylethynyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

nitromethane (75-52-5) + 1-(1H-benzo[d]-[1,2,3]triazol-1-yl)-3-phenylprop-2-yn-1-one (647833-19-0) → nitromethyl phenylethynyl ketone (116043-21-1)

Guidance literature:

nitromethane; With potassium tert-butylate; In dimethyl sulfoxide; at 10 ℃; for 0.166667h;

1-(1H-benzo[d]-[1,2,3]triazol-1-yl)-3-phenylprop-2-yn-1-one; In dimethyl sulfoxide; at 10 - 20 ℃; for 8h;

DOI:10.1021/jo051231x

Reference yield: 20.0%

4-phenylbut-1-en-3-yne (13633-26-6) → nitromethyl phenylethynyl ketone (116043-21-1) + 1-Nitro-4-phenyl-but-3-yn-2-ol (116043-22-2) + (4-Nitro-3-nitrooxy-but-1-ynyl)-benzene (116043-23-3)

Guidance literature:

With oxygen; dinitrogen tetraoxide; In diethyl ether; at -5 - 0 ℃;

upstream raw materials:

4-phenylbut-1-en-3-yne

nitromethane

1-(1H-benzo[d]-[1,2,3]triazol-1-yl)-3-phenylprop-2-yn-1-one