Technology Process of C16H17ClN2O2
There total 1 articles about C16H17ClN2O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
potassium phosphate; copper(l) iodide; trans-1,2-Diaminocyclohexane;
In
1,4-dioxane;
at 110 ℃;
for 18h;
Reagent/catalyst;
Solvent;
Schlenk technique;
Inert atmosphere;
DOI:10.1021/jo500064j
- Guidance literature:
-
With
trifluoroacetic acid;
In
dichloromethane;
at 0 - 20 ℃;
for 24h;
Inert atmosphere;
Schlenk technique;
DOI:10.1021/jo500064j
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: trifluoroacetic acid / dichloromethane / 24 h / 0 - 20 °C / Inert atmosphere; Schlenk technique
2.1: potassium phosphate; tris(dibenzylideneacetone)dipalladium(0) chloroform complex / tert-butyl alcohol / 6.5 h / 110 °C / Schlenk technique; Inert atmosphere
3.1: lithium diisopropyl amide / tetrahydrofuran / 1 h / -78 °C / Schlenk technique; Inert atmosphere
3.2: 0.75 h / -78 - 20 °C / Schlenk technique; Inert atmosphere
With
tris(dibenzylideneacetone)dipalladium(0) chloroform complex; potassium phosphate; trifluoroacetic acid; lithium diisopropyl amide;
In
tetrahydrofuran; dichloromethane; tert-butyl alcohol;
DOI:10.1021/jo500064j