Technology Process of 4,4'-bis(4-tert-butylstyryl)-2,2'-bipyridyl
There total 5 articles about 4,4'-bis(4-tert-butylstyryl)-2,2'-bipyridyl which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
4,4'-bis(diethylphosphonomethyl)-2,2'-bipyridine;
With
sodium hydride;
In
tetrahydrofuran;
at 20 ℃;
for 0.5h;
4-tert-Butylbenzaldehyde;
In
tetrahydrofuran;
at 20 ℃;
for 12h;
Reflux;
DOI:10.1007/s12039-011-0066-7
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: potassium dichromate; sulfuric acid / 16 h / 20 - 80 °C
1.2: 8 h / Reflux
2.1: sulfuric acid / 4 h / Reflux
3.1: sodium tetrahydroborate / ethanol / 3 h / Reflux
4.1: sulfuric acid; hydrogen bromide / 6 h / Reflux
5.1: chloroform / 3 h / Inert atmosphere; Reflux
6.1: sodium hydride / tetrahydrofuran / 0.5 h / 20 °C
6.2: 12 h / 20 °C / Reflux
With
sodium tetrahydroborate; sulfuric acid; potassium dichromate; hydrogen bromide; sodium hydride;
In
tetrahydrofuran; ethanol; chloroform;
DOI:10.1007/s12039-011-0066-7
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sulfuric acid / 4 h / Reflux
2.1: sodium tetrahydroborate / ethanol / 3 h / Reflux
3.1: sulfuric acid; hydrogen bromide / 6 h / Reflux
4.1: chloroform / 3 h / Inert atmosphere; Reflux
5.1: sodium hydride / tetrahydrofuran / 0.5 h / 20 °C
5.2: 12 h / 20 °C / Reflux
With
sodium tetrahydroborate; sulfuric acid; hydrogen bromide; sodium hydride;
In
tetrahydrofuran; ethanol; chloroform;
DOI:10.1007/s12039-011-0066-7
