4,4'-Dimethyl-2,2'-bipyridine

Base Information

• Chemical Name: 4,4'-Dimethyl-2,2'-bipyridine
• CAS No.: 1134-35-6
• Molecular Formula: C12H12N2
• Molecular Weight: 184.241
• Hs Code.: 29339900
• European Community (EC) Number: 214-483-2
• NSC Number: 3261
• DSSTox Substance ID: DTXSID3061552
• Nikkaji Number: J23.947J
• Wikidata: Q72469540
• ChEMBL ID: CHEMBL101165
• Mol file: 1134-35-6.mol

Synonyms:4,4'-dimethyl-2,2'-bipyridine

Chemical Property of 4,4'-Dimethyl-2,2'-bipyridine

Chemical Property:

• Appearance/Colour: Beige crystalline powder
• Melting Point: 174-176 °C
• Refractive Index: 1.6266 (estimate)
• Boiling Point: 309.3 °C at 760 mmHg
• PKA: 5.10±0.30(Predicted)
• Flash Point: 116.8 °C
• PSA: 25.78000
• Density: 1.06 g/cm³
• LogP: 2.76040
• Storage Temp.: Inert atmosphere,Room Temperature
• Water Solubility.: Soluble in ethanol, acetic acid, benzene, toluene. Highly soluble in water at pH < 2.
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 184.100048391
• Heavy Atom Count: 14
• Complexity: 161

Purity/Quality:

99% ^*data from raw suppliers

4,4''-Dimethyl-2,2''-bipyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xi,Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36-37/39

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Nitrogen Compounds -> Pyridines
• Canonical SMILES: CC1=CC(=NC=C1)C2=NC=CC(=C2)C
• Uses: 4,4'-Dimethyl-2,2'-bipyridine is used as a chemical Intermediate. It can be used for the determination of ferrous and cyanide compounds.

Technology Process of 4,4'-Dimethyl-2,2'-bipyridine

There total 35 articles about 4,4'-Dimethyl-2,2'-bipyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.4%

4-methylpyridine-1-oxide (1003-67-4) → 4,4'-dimethyl-2,2'-bipyridines (1134-35-6)

Guidance literature:

4-methylpyridine-1-oxide; With palladium on activated charcoal; at 65 ℃; for 6h;

With phosphorus trichloride; Temperature; Catalytic behavior;

Reference yield: 84.0%

benzyltri(2-(4-methylpyridyl))phosphonium bromide (126963-91-5) → picoline (108-89-4) + [2,2]bipyridinyl (366-18-7) + 4,4'-dimethyl-2,2'-bipyridines (1134-35-6)

Guidance literature:

With hydrogenchloride; In water; for 0.5h; Product distribution; Ambient temperature; variation of pH, temp. and time;

DOI:10.1016/S0040-4039(01)93895-X

Reference yield: 84.0%

benzyltri(2-(4-methylpyridyl))phosphonium bromide (126963-91-5) → picoline (108-89-4) + 4,4'-dimethyl-2,2'-bipyridines (1134-35-6) + C19H19N2OP

Guidance literature:

With hydrogenchloride; In water; for 0.5h; Ambient temperature;

DOI:10.1016/S0040-4039(01)93895-X

upstream raw materials:

picoline

2-Bromo-4-picoline

benzyltri(2-(4-methylpyridyl))phosphonium bromide

iron(III) chloride

Downstream raw materials:

1,2-bis(4′-methyl-[2,2′-bipyridin]-4-yl)ethane