N-(5-bromo-2-pyridinyl)-(2-(4-[(2-aminosulfonyl)phenyl]phenylcarbonyl)amino)-4-nitrophenylcarboxamide

Base Information

Chemical Name:N-(5-bromo-2-pyridinyl)-(2-(4-[(2-aminosulfonyl)phenyl]phenylcarbonyl)amino)-4-nitrophenylcarboxamide
CAS No.:330939-87-2
Molecular Formula:C₂₅H₁₈BrN₅O₆S
Molecular Weight:596.418
Hs Code.:

Synonyms:N-(5-bromo-2-pyridinyl)-(2-(4-[(2-aminosulfonyl)phenyl]phenylcarbonyl)amino)-4-nitrophenylcarboxamide

Suppliers and Price of N-(5-bromo-2-pyridinyl)-(2-(4-[(2-aminosulfonyl)phenyl]phenylcarbonyl)amino)-4-nitrophenylcarboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(5-bromo-2-pyridinyl)-(2-(4-[(2-aminosulfonyl)phenyl]phenylcarbonyl)amino)-4-nitrophenylcarboxamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(5-bromo-2-pyridinyl)-(2-(4-[(2-aminosulfonyl)phenyl]phenylcarbonyl)amino)-4-nitrophenylcarboxamide

There total 6 articles about N-(5-bromo-2-pyridinyl)-(2-(4-[(2-aminosulfonyl)phenyl]phenylcarbonyl)amino)-4-nitrophenylcarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

: 2-amino-5-bromopridine

: 358661-72-0
methyl 2-(4-[(2-t-butylaminosulfonyl)phenyl]phenylcarbonyl)amino-4-nitrobenzoate

: 330939-87-2
N-(5-bromo-2-pyridinyl)-(2-(4-[(2-aminosulfonyl)phenyl]phenylcarbonyl)amino)-4-nitrophenylcarboxamide

Guidance literature:: AlMe₃; In hexane; dichloromethane; water; acetonitrile; trifluoroacetic acid;

Reference yield:

: 1072-97-5
5-bromo-2-pyridylamine

: 330939-87-2
N-(5-bromo-2-pyridinyl)-(2-(4-[(2-aminosulfonyl)phenyl]phenylcarbonyl)amino)-4-nitrophenylcarboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: AlMe₃ / CH₂Cl₂ / 12 h / 20 °C

2: TFA / 2 h / Heating

With trimethylaluminum; trifluoroacetic acid; In dichloromethane;
DOI:10.1016/j.bmcl.2003.11.079

Reference yield:

: 309930-58-3
4-{2-{[(tert-butyl)amino}sulfonyl}phenyl}benzoic acid

: 330939-87-2
N-(5-bromo-2-pyridinyl)-(2-(4-[(2-aminosulfonyl)phenyl]phenylcarbonyl)amino)-4-nitrophenylcarboxamide

Guidance literature:: Multi-step reaction with 4 steps

1: SOCl₂ / 2 h / Heating

2: pyridine / CH₂Cl₂ / 12 h / 20 °C

3: AlMe₃ / CH₂Cl₂ / 12 h / 20 °C

4: TFA / 2 h / Heating

With pyridine; thionyl chloride; trimethylaluminum; trifluoroacetic acid; In dichloromethane;
DOI:10.1016/j.bmcl.2003.11.079